and some of its Products of Decomposition. 337 



Glycocoll contains the elements of furaaric acid and ammonia. 

 If the former alone be taken from hippuric acid there remains 

 benzamide. 



C 13 H 8 N0 5 -G 4 H0 3 =C I4 H 7 N0 3 . 



, , r - 



Hippuric acid. Fumaric acid. Benzamide. 



Physiological Relations of Glycocoll. 



Ure* observed that when benzoic acid is taken into the ali- 

 mentary canal, it reappears in the urine as hippuric acid. This 

 at the time startling announcement, has been verified in the most 

 satisfactory manner by Garrod,f by Keller,J in the laboratory of 

 Prof. Booth, Philadelphia, and in the Giessen laboratory. 



Pettenkofer$ found in the medical examination of the urine of 

 a girl, who suffered from St. Vitus' dance, and ate nothing but 

 apples and bread, an unusually large quantity of hippuric acid. 

 With the return to animal food, the abnormal proportion of this 



^redient diminished. 



The occurrence of this acid in the urine of horses and cattle, 

 and of men who live chiefly upon vegetable food, is well known. 



These facts taken in connexion with the newly developed con- 

 stitution of hippuric acid, suggest an inquiry that may not be 



without interest, viz : — 



Are glycocoll and benzoic acid, as such, a part of the tissues of 

 the animal body 1— of the albumen, caseine, and fibrine, sup- 

 plied to it as food ? and finally of the corresponding bodies in 



the seeds and juices of plants. . 



1. Braconnot obtained glycocoll by treating glue with sulphuric 

 acid ; Mulder and Boussingault by treating glue with caustic pot- 

 ash ; and Keller obtained it by treating the tissues or the fluids ol 



the body with benzoic acid. 



firmly 



the destructive action of sulphuric acid and potash with the aid 

 °f heat, than the remaining members composing glue. 1 nese 

 Were for the most part oxydated or consumed. 

 The albumen, fibrine, and caseine received into, and secreted 



parts 



7 



return 



ammonia 



*ere derived. They commence oxydation. This, however, 

 does not affect all members of the complex compounds ■"«-." 



s °me instances 



ppeann 



*L'I„sutut, No. 399, 279, and No. 401, 294. Journal de Pharmacy, xxviii, 



P-646. 



18 44, s. 879. 

 § Liebig's Ann., Bd.liii, s. 86. 

 Second Seriks, Vol. IV, No. 12— Nov., 1847. 43 



