23.6 Leach et al: Hookworm Infestation 473 



carbon tetrachloride and got along very well for two days, 

 showing no reaction save a rather large amount of mucus in 

 his stool. Two days after treatment his stool was found to 

 contain free blood and he passed a clot similar to the one passed 

 by the preceding subject. He did not complain of pain or dis- 

 comfort of any kind and showed no other ill effects. He gave 

 a history of cholera some years previously. He drank tuba in 

 moderation. 



These two cases, of course, raise the question of the possible 

 ill effects of carbon tetrachloride on an intestine already 

 weakened by some infectious process. It, therefore, becomes a 

 matter of interest to inquire specifically into the performance 

 of the men in this series, twenty-eight in number, from whom 

 we elicited a history of infectious intestinal affections in the 

 past. The observations on these subjects we have tabulated in 

 Table 5, to admit of ready inspection. 



It should be noted that in Table 5 we have not attempted to 

 classify the dysenteries, although it is highly probable that 

 most of them were bacillary in origin. Moreover, it is of pass- 

 ing interest to note that of the seven carriers of Entamoeba 

 histolytica not one gave a history of dysentery. 



The intestinal conditions cited in Table 5 are summarized 

 in Table 6. 



Table 6. — Summary of intestinal conditions set forth in Table 5. 



Condition. Cua. 



Cholera 4 



Dysentery 11 



Dysentery and cholera 3 



Diarrhoea 1 



Entamoeba histolytica carrier (no dysentery) 7 



Entamoeba histolytica carrier; cholera (no dysentery) 1 



Typhoid fever 2 



On reviewing the data in Table 5, it will be seen that only 



two subjects showed any marked general reaction to the drug. 



Both these men were carriers of Entamoeba histolytica who 



gave no history of dysentery. It will be further noted, on 



comparing the data contained in Tables 5 and 10, that of the 



men with histories of former intestinal affections, numbering 



28 per cent of the total number of men studied, only ten passed 



excessive quantities ( + + to + + + + ) of mucus in their stools. 



That number represents 22.7 per cent of the men who passed 



excessive quantities of mucus after treatment. 



In interpreting this, it must be realized that estimations of 

 the relative amounts of mucus in the different stools were not 



