23,5 Leach et al.: Hookworm Infestation 489 



tions of 90 per cent or more were made on fifty-nine men. In 

 only two cases were low erythrocyte counts and haemoglobin 

 estimations associated with worm counts of 100 or more, as is 

 shown by Table 12. Particular attention is drawn to case 14658 

 in that table, in which the highest worm count is seen to be 

 associated with the highest erythrocyte count and one of the 

 highest haemoglobin estimations. On screening the stools of 

 this man 1 Ancylostoma and 354 Necator were recovered. 



nd haemoglobin 



Worn, count. 



Erythmcy*.. 



*-**, 





4,050 



::; 



» 



difficult to say whether or not these high erythrocyte 

 counts are due to increased oxidation in the Tropics. On the 

 other hand, it should be noted that these counts were made 

 during the month of May, which is the height of the hot, dry 

 season in Manila, in consequence of which there may be an 

 association between the polycythaemias and a decreased fluid 

 content of the blood. These are points that can only be deter- 

 mined by extensive investigation. It is suggestive of a lack 

 of reaction, or a failure on the part of the subject to experience 

 serious effects from the presence of intestinal parasites. Only 

 four of the men had erythrocyte counts that fell below 4,000,000, 

 and only a like number exhibited a haemoglobin percentage that 

 fell below 70. 



These figures are startlingly at variance with those we ob- 

 tained on study of the blood of eleven cases of hookworm anaemia 

 in Cebu.(8) l n that series the total erythrocyte counts ranged 

 from 1,380,000 in a heavily infected case, up to 3,330,000 in a 

 case that already had been treated with chenopodium but still 

 retained a light infection. In the Cebu series the haemoglobin 



