498 The Philippine Journal of Science mz 



of carbon tetrachloride to each 6 kilograms of body weight. The 

 men were watched, and the first stool passed by each was sent 

 to the laboratory for screening. The drug was administered 

 at 1.40 o'clock in the afternoon. Every man in the group had 

 defecated before 2.45 o'clock. The results are shown in Table 

 16. It will be seen that 17 per cent of the hookworms were 

 eliminated in the first stool. 



Table 16. — Stool findings in six cases one hour after treatment. 



The findings on screening the stools of the hookworm-positive 

 cases are shown in Table 17. These are recorded day by day, 

 together with the amount of drug administered. It will be seen 

 that there appears to be no correlation whatever between the 

 quantity of carbon tetrachloride administered and the propor- 

 tionate number of worms recovered on the first day. 



Of the total number of worms passed by these men in the 

 stools collected during the three days succeeding treatment, 

 97 per cent were contained in the stools passed during the first 

 twenty-four hours. In fact, 63 per cent of the men seemed to 

 have unburdened themselves of their total stock of worms in 

 this time, for none were found on the subsequent days. In only 

 two instances did we recover worms from stools passed on the 

 third day. The stools of seven men were negative throughout. 

 It has been noted that the lightly infected cases seem to be 

 the more difficult to clear. It is highly probable that these 

 cases were lightly infected and that the worms were passed 

 either in a condition of extreme maceration, or were lost in 

 particularly bulky stools, of which there were many. Prisoners 

 are fed unpolished rice at Bilibid, and the stools are usually 

 full of husks which add great difficulties to the search for worms. 



The dosages of carbon tetrachloride administered to the sub- 

 jects from whom we failed to recover hookworms on screening 

 ranged from 6.6 to 11.2 cubic centimeters. 



