502 The Philippine Journal of Science 1923 



When the drug acts at all, it seems to act effectively, for nearly 

 all the worms recovered within the first few hours after treat- 

 ment were dead, the few that were recovered alive being mori- 

 bund. This may in itself be a danger as leading to the retention 

 of dead worms the presence of which in the intestinal tract may 

 give rise to unpleasant symptoms, as is pointed out by Haughwout 

 and Ash. (5) 



The location of Trichuris in the large intestine is unfavorable 

 as regards the application of the drug. The drug reaches the 

 lower intestine in a state of dilution and at a time when peri- 

 stalsis has been stimulated to a marked degree. The consequence 

 is that it has little time to exert itself on the worms, but is 

 hurried past them in a weakened concentration. The surprising 

 thing is that it is as efficient as our figures show it to be in cer- 

 tain cases. We are led to suspect, though we have no definite 

 data to support the supposition, that the cases in which it seemed 

 to act most efficiently were afforded by patients whose bowels 

 did not move so briskly or so promptly as did those of the other 

 men. The observations on the cases of Ascaris and Trichuris 

 infestation are recorded in Table 19. 



Table 19.— Results 







of A 



,,„,,■ 



and Trichuris infestations. 



[ 



D «, 



4—* j T„ A „U. 



Final stool 



2£ 



s 



25? 



25! 



duy. 



.i'i* ' 



ii'c 



:i:i 



: 



: 



: 



; 



• 



I 



Negative. 

 Do. 



3 



; 



; 















■ 



• 



\ 



14708. 











3 



: 



• 









14718. 



jj™' - 



"I 



„ 



« 



\*™\ 



