512 The Philippine Journal of Science 



very careful inquiry. In our opinion, the drug should be ad- 

 ministered several days before the administration of an anes- 

 thetic, in order that the liver may entirely recover from the 

 stimulating effects of the carbon tetrachloride. This we deem 

 especially important if it is desired to administer chloroform. 



Among the subjects for future investigation that are sug- 

 gested by our work we may mention the following: Is the ad- 

 ministration of the drug to persons about to undergo surgical 

 operation fraught with any dangers? Are untoward hepatic 

 symptoms likely to arise when an anesthetic is later admin- 

 istered? Would there be a tendency toward the development of 

 ileus? Do any racial idiosyncracies to the drug exist? How is 

 the drug eliminated? What are the effects of the drug on the 

 cardio-vascular system? Definitely, what is the action of this 

 drug on Trichuris? 



Lastly, further pathologic work should be done with especial 

 attention to the kidneys and liver. Such studies should be 

 made with strict attention to the prevalence of mild to subacute 

 conditions commonly found in the kidneys and livers of natives 

 of tropical countries, which not improbably bear a more or less 

 ItT 1 V 1 ? prevaiIin * in testinal Pathology in these 



people. Lesions of the liver should be studied with an eye to 

 the topographic relations of the microscopic lesions 



b£Td TZ' ? EST °V ^ inflU6nCe ° f tr °P icaI "»W™» <>n the 

 2 D^hhLv ?^ J ,° Urn -l T °V- Di *- & Prov. Med. 2 (1914) 41-54. 



r^Tf \ an * BURGESS ' E - The action of carbon tetrachloride 

 o r™J™ T Gr ' Med - Journ - No - 3228 (!922) 907-908. 



Z£ 'r^L*^ SEV T- VICT ° R - Ex *~ns of the blood with 



^ B 4 (1909)277 ^ ^ ° f ^^ PhiliP ' J ° Urn - 



4 ' H Jo„^ W p T 't ^\ G ' S ° me less famiIiar ««"** of parasitology. 

 Journ. P. I. Med. Assoc. 1 (1921) 93-99. 



«TT T ' FRA . NK G -' and ASH ' J ' EARLE - A «tudy of intestinal 



parasitism ln American and European children in the Philippine 



Islands. (In preparation.) 

 LA d**T T ' S -M. Carbon tetrachloride in the treatment of hookworm 



disease. Observations in twenty thousand cases. Journ. Am. Med. 



Assoc. 79 (1922) 2055-2057. 

 7. Leach, C. N. Carbon tetrachloride in the treatment of hookworm disease. 



Journ. Am. Med. Assoc. 78 (1922) 1789-1790. 



n™' N *%?* N - Schwartz, Benjamin; and Leach, Florence 

 xon, with the cooperation of Haughwout, Frank G. Hookworm 



tr*T,L C \ iniCal Gntity in the PhiIi PPine Islands. Philip. Journ. 



Sci. 23 (1923) 105. 

 9. Smilue, W G. and Pessoa, S. Treatment of hookworm disease with 



carbon tetrachloride. Bull. International Health Bd. 3 (1922) 11. 



