Samson and Limkako: Creosote in Leprosy 

 Table 7.— Duration of reactions. 



As regards the type of reaction, those in Groups I and II 

 were essentially similar, with 65 per cent of Type 4; 14 and 18 

 per cent of Type 3, and less of the others. In Groups III and 

 IV Type 4 reactions predominated still more markedly, with 

 81 and 80 per cent,, respectively. There was but one reaction 

 of Type 2 and none of Type 1. In other words, practically no 

 exacerbation of old lesions was produced by the creosoted esters, 

 and but 15 and 20 per cent, respectively, had fever with the new 

 lesions. The reactions caused by these preparations were 

 milder than those produced by the plain preparations. 



On the other hand, the duration of reaction with the plain 

 preparations is very distinctly less than with the creosoted 

 However, in view of the mildness of the reactions, it is believed 

 that this greater duration was not harmful. General statistics 

 of the Culion work 3 indicate that, on the whole, the reactions 

 of longer duration are harmful; the figures for improvement 

 given below indicate that this was not the case in the present 

 experiment. 



RESULTS OF TREATMENT 



The condition of the disease at the end of six months has been 

 compared with that at the beginning of the present treatment 

 based on our records and the opinions of the patients and of 

 ourselves. The findings are given in Table 8. Here all cases 

 are classified as apparently negative, moderately improved, 

 slightly improved, stationary, and worse. ...... 



The total improved, stationary, and worse are plotted m fig. 2. 



According to these figures improvement under treatment with 

 the creosoted preparations was distinctly greater than with the 

 plain. 



The totals (not shown in the table) were 51 per cent for the 

 plain and 65 per cent for the creosoted. Comparing the four 



'Personal communication 



from the acting chief physician; report 



