i and Limkako: Creosote in Leprosy I 



Table 9. — Percentages of patients who showed change in weight. 



-* 



Cases. 



Increase. 



Ma rk ed. 



Moderate. 



Slight. 



Tot.,. 



! 



1 



5 





184 

















Decreaae. 





Marked. 



Moderate. | Slight. 



TotoL 



j 



18 8 



ti 



4.1 



Si! 





s 













CONCLUSIONS 

 From the results of the observations that have been made to 

 date, given herein, the following tentative conclusions may be 

 drawn: 



1. Creosote given in small amounts by mouth to lepers serves 

 to stimulate the appetite, resulting in increased weight and 

 increase in the improvement rate in cases under chaulmoogra 

 treatment. 



2. Creosote introduced into the muscle causes marked local 

 inflammation, which in some way is to some extent prevented 

 or reduced by camphor. 



3. A greater percentage of improvement has been secured 

 with the admixture of a moderate amount of creosote in chaul- 

 moogra ethyl ester. 



4. Large amounts of creosote, with the addition of camphor 

 to reduce irritation, give less beneficial results, perhaps because 

 of the injurious effect of the camphor. 



5. Creosote preparations apparently cause lepra reaction in 

 a larger number of patients than do the plain preparations, but 

 these reactions are not severe and apparently not harmful. 



ACKNOWLEDGMENT 



We wish to express our appreciation to Dr. H. W. Wade, 

 acting chief physician of the Culion Leper Colony, at whose 

 suggestion this work was undertaken, and who has assisted us 

 in the analysis of the results and the preparation of this report. 



