The Philippine Journal of Science iw» 



of clavus and of leprotic adenitis showed no im- 



dosage. On the contrary, none of the ten patients receiving 

 the highest average doses per injection were improved m any 

 respect. Five of the six deaths are included among these ten; 

 only three finished the experiment ; the rest had to be dropped. 



UNTOWARD EFFECTS OF TREATMENT 



Twenty-three of the leprosy patients showed ill effects of some 

 kind or other and only seven remained free. Table 6 gives all 

 such symptoms observed. 



Table 6.— Untoward effects of treatment in leprosy cases. 



The commonest reaction was a brief slight fever that appeared 

 a few hours after injection. This occurred thirty-four times. 

 The fever seldom rose higher than 38° C. and was discovered 

 only by taking the temperature as a matter of routine. The next 

 commonest complaint was headache, which was rather severe at 

 times. This was observed twenty-five times in eleven of our 

 patients. Nine complained of general weakness after injection ; 

 this occurred nineteen times, usually accompanied by slight 

 dizziness. Chill a few minutes after injection was occasionally 

 observed. Nausea was noticed only twice. The nonleper had 

 slight fever following an injection once during the period. 



