570 



The Philippine Journal of Science 



early part of the experiment and before the appearance of con- 

 vulsive symptoms the recording of the pulse, respiration, and 

 temperature constituted a part of the regular procedure. Close 

 observation was made for any increase in reflexes that might be 

 manifested, and the results of such observations were carefully 

 noted. The effects of strychnine produced in the varying doses 

 employed by the various channels of administration are shown 

 by the data which follow. The experiments were so conducted 

 that two dogs received the drug by mouth ; four, subcutaneously ; 

 two, intravenously ; three, by rectum ; and one, intramuscularly. 



RESULTS 



The results of these experiments are given in five tables. 

 Table 1 gives the results of administration by mouth. The 

 mouth was carefully lubricated with molasses and the calcu- 

 lated amount of strychnine sulphate was given by means of a 



by mouth. 



May22 6, 



May 29..... 6, 



