QA Referat?. 



forms lacking the factor E which, when present, turns the eye dark and 

 at the same time intensifies the coat colour. These corresponding forms may 

 be set out as follows : 



Dark-eyed series Pink-eyed series 



Agouti EGBCh eGBCh . pink-eyed agouti 



Cinnamon agouti EGbCh eGbCh . pink-eyed, cinnamon agouti 



Black EgBCh egBCh . blue-liiac 



Chocolate EgbCh egbCh . champagne 



An additional form occurs in the lighter series owing to the fact that the 

 heterozygous eeggBbChCh, is chocolate-lilac in colour, and quite distinct from 

 the homozygous blue-lilac. Yellow mice may also be pink-eyed, and though 

 in this variety also the colour is often more dilute when associated with the 

 pink-eye, it may nevertheless be as dark as in the dark-eyed yellow. 



The dilute colours in the pink-eyed series are entirely distinct from the 

 dark-eyed dilute forms, blue agouti, blue, and silver-fawn. These last owe 

 their paler colour to the lack of a distinct factor for intensification, D. The 

 factor D may however be borne by the pale pink-eyed forms, so that fuU 

 black may result from the mating together of blue and champagne. 



Other experiments were made with sables, j-eUow mice with a dark 

 streak down the mid-dorsal region. The genetic behaviour of these mice is 

 complicated, for while some of the results suggest that sable is recessive to 

 yellow, others show that sables can throw some yellows. As in the case of 

 yellows no homozygous sable mice were met with. R. C. Punnett. 



Castle, W. E., and Phillips, J. C. On Germinal Transplantation in Vertebrates. 



Carnegie Institution, Publ. Xo. 144, Washington, 1911. 



The authors made a number of experiments on ovarian transplantation 

 in guinea-pigs, and also a few in rabbits. In most cases the grafted ovary 

 failed to live, or else regeneration of the original ovary occurred. In two 

 individuals however the operation was successful. The experiments were 

 so arranged that the grafted ovary contained a dominant factor which was 

 not present in the recessive parent from which the gland had been removed. 

 Thus the ovaries of an albino guinea-pig were cut out and in their stead 

 were grafted those from a female belonging to a pure black strain. The albino 

 female with her "black" ovaries was crossed with an albino buck and produced 

 si-x young, all of which were black. With her own ovaries she would have 

 given nothing but albinos when mated with an albino buck. Hence her 

 functional ovary must be regarded as that grafted in from the black female, 

 and post mortem examination shewed this to be certainly the case. 



As the result of their experiments the authors are on the whole opposed 

 to the view that the hereditary properties of a grafted ovary are affected 

 by the transplantation. Some criticism is given of the experiments of Magnus 

 and of Guthrie whose conclusions the authors do not consider to be justified 

 by their facts. 



Some experiments were also made on the grafting of testicles in rats. 

 In no case did the grafted organ live long in its host, and the experiments 

 were soon discontinued. 



The paper contains a brief review of the work hitherto done in grafting 

 the sex glands, together with a bibliography of the subject. 



R. C. Punnett. 



