230 REPORT—1868. 
100 grammes of dry food was on the first day 5-64 grammes, on the second 
day 30-+ grammes, and on the third day 6-9 grammes. The observations 
recorded in Table XVI. show, however, that the biliary secretion was in the 
case of dog 7 greatly influenced by the amount of dry food; it will there be 
seen that the amount of bile secreted was greatly diminished by starvation. 
It therefore appears that the biliary secretion is in some cases greatly in- 
fluenced by the amount of food taken, while in other cases it is not influenced 
at all. 
RELATION BETWEEN BILIARY SECRETION AND WerEIGHT or ANDMAL. 
The close relation supposed to exist between the amount of the biliary 
secretion and the size or weight of the animal has not been supported by the 
observations of the Committee. The amount of bile secreted for every kilo- 
gramme weight of dog varied greatly in different cases, as the following 
Table shows. 
Taste XXI.—Average amount of Bile secreted per Kilogramme Weight of 
the Dogs observed by the Committee before drugs were administered. 
No. of dog. | Fluid bile. | Bile solids. 
germs. grm 
Wop, Wieser 6-47 0-412 
i, aia 7:82 0:28 
ar Pee 527 0-34 
mi iS wetarked 5°76 0-293 
ir terti oe: 3°53 0°146 
Bl ga nt 21:8 0-301 
LA Gana 20-66 0-818 
5; b (fee aes 4-64 0:23 
G92 Bid, 9-24. 0305 
saps eee 10:2 0°58 
The foregoing Table gives the per kilogramme biliary secretion only when 
the dogs were healthy, and not subjected to the action of drugs. The 
Table shows how fallacious are the calculations which have been made re- 
garding the human biliary secretion, from observations upon dogs, by Bidder 
and Schmidt. We at one time thought that the large secretion in the case 
of dog 5 might be due to the fact that it ate liver instead of muscle like the 
other dog 9; it secreted nearly as much bile, however, when, instead of 
liver, it ate spleen. Moreover, such an explanation could not be offered in 
the case of dog 6, which secreted nearly as much bile per kilogramme as 
dog 5. This dog was fed on a diet the same as that given to dogs 1, 2, 3, 
and 4, so that no peculiarity in the nature of the diet can be alleged as the 
cause of the large secretion in the case of dog 6. Nor can the quantity of 
food it took have been the cause; for the animal secreted more bile per 100 
grammes of dry food than any other dog under the observation of the 
Committee. Seeing, then, that in the case of dog 6 neither the food nor the 
size of the animal can at all account for the amount of bile secreted, we 
must look for the cause elsewhere. One member of the Committee sug- 
gested that perhaps the amount of bile secreted may have a closer relation 
to the size of the liver than to the size of the animal. Unfortunately this 
idea did not oceur until after dog 6 was killed, so that its liver was not 
weighed ; but there is this much to be said, that dog 6 was a young dog (six 
months’ old); and we know that in young animals the liver is larger in pro- 
