1923] Wagener: Leishmania tropica and Leishmania infantum 485 



SUMMARY 



The intradermal injection of alkaline extracts of Leishmania 

 tropica or Leishmania infantum will produce a local reaction in the 

 skin of a sensitized rabbit. This reaction is characterized by an 

 erythematous papule which reaches its height in 48 hours and persists 

 from 72 hours to 5 days. 



The injection of a concentrated extract produces necrosis aaid 

 sloughing. Normal rabbits show no reaction. 



The reaction in immune or sensitized rabbits is not specific for 

 the homologous species of Leishmania. 



Transmitted October 8, 192S. 



From the Depaktments op Zoology and of Hygiene, 

 ■University of California. 



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