1913] Siveet: Epithelioma of the Common Fowl 49 



(fir) In response to an inoculation with epitheliom;i eon- 

 tagiosum there is produced a specific antibody in the blood of 

 the host. 



2. Epithelioma eontagiosum and roup are entirely independ- 

 ent diseases. 



(a) Epithelioma eontagiosum is constantly and readily trans- 

 mitted by inoculation, while roup is not (Ward). 



(&) Immunity conferred by an inoculation with the virus ol' 

 epithelioma eontagiosum does not prevent the contraction of 

 roup. 



(c) Under the conditions of our experiment, epithelioma eon- 

 tagiosum was not fatal to mature fowls, while all that contracted 

 roup died. 



3. The cell inclusions present in the hyperplastic epithelial 

 cells of epithelioma eontagiosum show changes which may 

 perhaps represent stages in the development of a protozoan 

 parasite, but we are unable to so connect them that a complete 

 life-cycle is definitely established. 



LITERATURE CITED 



Apolant, H. 



1003. Beitrag zur Ilistologie der Gefliigelpocke. Virchow 's Arch., 

 174, 86-9.5. 



BOLLINGEK, A. 



1873. Ueber Epithelioma eontagiosum beim Haushulm und die 

 sogenannten Pocken des Gefliigels. Yirchow 's Arcli., 58, 

 349-361, pi. 9. 



BORDET, J. AND FaLLY, V. 



1910. The bacterium of fowl diphtheria. Jour. Comp. Path, aud 

 Therap., 23, 565-.568. 



BORREL, A. 



1903. Epithelioses infectieuses et epitheliomas. Ann Inst. Pasteur, 

 17, 81-122, pis. 1-6. 



Burnet, E. 



1906. Contribution a 1 'etude de 1 'epithelioma contagieux des oiseaux. 



Ann. Inst. Pasteur. 20, 742-76.5, 1 fig. in text. 



Carnwath, T. 



1907. Zur Aetiologie der Hiihnerdiphtherie und Gefliigelpoeken. 



Bull. Inst. Pasteur, 5, 976-977. 



