eo eee 
ON ANAUSTHETICS. 999 
A regulating drop bottle is used capable of delivering the mixture in 
isolated drops, in a rapid series of drops or in a continuous stream (fig. 2). 
During the first two minutes the mixture is poured upon the mask in 
such smail quantities at a time that there is never more than a quarter of 
the mask moist. From this time it is added more freely until, roughly 
speaking, in the case of men the whole surface of the mask, in the case 
of women three-quarters of the surface, and in the case of children one 
half of the surface, is kept moist with the liquid. Asa rule at least four 
minutes pass between the beginning of the administration and the 
moment when the maximum quantity to be used is upon the mask. 
3. The Nature of the Cases in which the Method has been employed. 
_ The cases in which the method has been employed include a variety of 
operations, comprising examples of almost all the graver abdominal 
procedures, which were particularly chosen as providing a severe test of 
the efficacy of any anesthetic and method. Thus, pan-hysterectomies, 
removal of double pyo-salpinx, difficult appendicectomies, excisions of 
rectum, and ‘complete’ amputations of breast figure amongst the 
cases. Moreover, the patients comprised individuals of widely differing 
physique and states of health. They ranged from the very healthy mus- 
cular police-sergeant to that of the emaciated, anemic young woman, 
the subject of long-standing colitis. Several so-called ‘ bad subjects ’ 
have been anzsthetised with success; for example, heavily built, florid, 
thick-necked men, with irritable throats and nasal obstruction, patients 
with ill-developed lower jaws, &c., subjects who invariably give trouble 
under ‘ gas and ether.’ In age patients have ranged from the infant of 
fourteen months to old persons over eighty years of age. Several patients 
were markedly alcoholic, others were asthmatic and orthopneeic; one 
patient was suffering from pneumonia, and in this case oxygen was 
simultaneously administered through a tube passing through the mask. 
One case, that of a young woman who underwent laparotomy for the 
removal of double pyo-salpinx, was a good example of the subject who, 
originally favourable, is at the time of operation in a condition of extreme 
