428 



rEpobts on the state of science. 



(4) The above holds good for kidneys without drugs (two experiments), 

 and for kidneys perfused with 0'2 per cent, sodium sulphate in saline 

 (two experiments). The experiment which has given the most marked 

 result was as follows : — • 



Oxygen Consumed per Minute. 



Perfused with Norinal Saline through Aorta . . . 0-0025 c.c. 



„ „ „ „ Renal Portal . , 0-0008 c.c. 



„ „ „ +0-1 Na^So^ „ , . 0-0018 c.c. 



„ „ „ „ through Aorta . 0-0049 c.c. 



In the last case only was there diuresis. Subsequent injection through 

 the inf. vena cava showed that the kidneys only were contributing to the 

 fluid collected for analysis. 



III. The Heart. — It has been found possible to perfuse the heart with 

 undiluted blood by the method devised by Heymans — namely, to lead 

 blood from the carotid artery of a large dog into the aorta of a small dog 

 or puppy, to allow it to go through the coronary system of this animal, and 

 to lead it back from the pulmonary artery to the jugular vein of the large 

 dog. The technique of Heymans has been improved for blood-gas 

 purposes by rendering the blood non-coagulable by the injection of 

 hirudin (see 1905 report). 



The gaseous metabolism of the heart is reduced by influences which 

 diminish tlie rate or amplitude of the heart's contraction or the tonus of 

 its muscle, e.g., pilocarpine, KCl, vagus stimulation ; whilst its gaseous 

 metabolism is increased by drugs which have a contrary eflect, adrenalin, 

 atropine after pilocarpine, BaClo after KCl. 



The rate of blood-flow through the coronary system varies, other 

 things being equal, with the amount of CO., produced by the heart. 



IV. Apparahis has been devised for estimating the quantity of oxygen 

 dissolved in 10 c.c. of salt solution. The following figures give an idea of 

 its accuracy : — 



The Committee ask for a further grant of 45?., the grant of last year 

 having all been expended. 



The State of Solution of Proteids. — Fourth Report of the Committee, 

 consisting of Professor Halliburton (Chairman), Professor Way- 

 MOUTH Keid (Secretary), and Professor Schafer. (Dratvn np by 

 the Secretary.) 



Since the experiments of the past session are not yet completed, a full 

 report must be delayed till a future occasion. 



The main object of the experiments has been to atternpt to construct 



