83 



20. Über die Brunn ersehen Drüsen des 

 Meerschweinchens. 



(Zu Seite 50, Fußnote 3.) 



„In the guinea pig (Cavia cobaya) the glands of Brunner 

 are feebly developed, althoug they extend a considerable distance 

 into the duodenum, aecording to Kuczynski (1890) 10 cm. 

 Even at its thickest part, near the sphineter pylori, the Iayer 

 may be not more than 0,25 mm in thickness. For a distance 

 of about 7 mm it forms a fairly continuous layer of thin 

 lobnies, but beyond this point the lobules become very small 

 and odeur at inereasingly greater intervals. Each lobule is 

 composed of a Cluster of branching tubules connected by a 

 short duet with the bottom of a gland of Lieberkühn. 



„The tubules are composed of cuboidal to cylindrical or 

 prismatic cells, varying in height from 9,5 ;x in the small 

 flattened tubules of the distal lobules to 14 \x to 18 \x in the 

 proximal lobules. The nuclei of these cells are irregularly 

 crescentic in shape and are located in the extreme outer ends 

 of the cells. The body of the cell exhibits the usual transparent 

 reticular appearance when examined in preparations stained in 

 iron haematoxylin. There is usually in the middle of the cell 

 a slight condensation of the cytoplasm, a Suggestion of the 

 subdivision of the secretion into two masses. In some of the 

 cells, particularly in those of the duets near the points where 

 they are about to open into the glands of Lieberkühn, 

 and in those forming the tubules of the small distal lobules. 

 a very obvious band of this Condensed cytoplasm may Stretch 

 across the cell. In the latter case the cytoplasmic trabeculae 

 which separate the granules of the proximal mass are coarser 

 in texture and form smaller meshes than those of the distal 

 zone. These facts indicate the probability that the mechanism 

 of secretion in the glands of Brunner of the guinea pig is 

 similar to that in the corresponding glands of the opossum and 

 many other mammals. 



„The cells of the pyloric glands immediately adjacent to 

 the pylorus are exaety similar to those of the glands of 

 Brunner. The glands more remote from the pylorus are formed 

 of wedge-shaped cells 12,8 \x to 14,3 ;x in height, surroun- 

 ding an extremely small luraen. The nuclei of these cells are 

 spherical or oval in shape and located in the base of the cell. 

 The secretion, which stains readily in stronger muchaematein, 

 oecupies a considerable portion of the cell inclosed by the 

 meshes of a cytoplasmic reticulum. In many cells, however, 



