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REPORT 1878. 



were conducted in a similar manner, except when I filtered in order to get rid of 

 epithelium, a circumstance noted in my tabular statement of results, in which case, 

 of course I employed the constant for filtered water. I may here note that I ex- 

 amined the deposit from the water of the bath under the microscope, and found it 

 to contain scarcely a trace of anything but epithelial scales. On comparing my 

 experiments with those of Funke, we find that the quantities of nitrogen obtained 

 by Funke are much greater than mine. This difference may arise from the circum- 

 stance noted already, that Funke's experiments were conducted under the con- 

 ditions of more or less violent exercise, which I, accepting the views of Liebig, so 

 strongly supported by the recent experiments of Professor Flint on the pedestrian 

 Mr. Weston, believe to be always accompanied by waste of muscular tissue, and 

 consequent increased execretion of nitrogen. I am aware that this view has been 

 controverted by the experiments of several eminent physiologists, but I believe that 

 my work tends somewhat to confirm it, though indirectly. I believe that the cutaneous 

 excretion of nitrogen in normal healthy conditions is but small. But in my table 

 will be found the results obtained from a patient suffering from Bright's disease 

 (marked [c]), showing an excretion of nitrogen more than double the average 

 amount in my own case (marked [«]). I note that in case [6] the renal excretion 

 of nitrogen was considerable, increased by the use of the hot-air bath, a result I 

 conceive of great importance, due, I believe, to the temporary febrile condition 

 induced by the bath, evidenced by the increased rate of pulse and bodily tempera- 

 ture. I have since found this view confirmed by the experiments of G. Von Schleich, 

 of Tiibingen, showing an increased excretion of urea caused by the use of the 

 ordinary hot-water bath. But I have not as yet had an opportunity of making 

 further researches, on this point. I have again to thank my friend Professor J. 

 Emerson Reynolds, under whose guidance my experiments were conducted, for his 

 valuable and kind assistance. 



* Experiments 6 and 7 made on the same day. 

 t Experiments 8 and 9 made on the same day. 



J The mean renal excretion of nitrogen for three days immediately preceding 

 was only 14-4 grammes. 



