: 
TRANSACTIONS OF SECTION I. 981 
sections together. (8) Adjust wax plates in pairs, fix to one another by piercing 
with hot tools and continue this till cell built up. (9) Smooth outlines with hot 
brass instruments and give final touches with a knife, controlling each touch by 
carefully focussing in the microscope the level of the proximal and distal ends of 
each process. 
Some New Observations Obtained by this Method.—(1) The unipolar cells of 
spinal ganglia and multipolar cells of sympathetic ganglia are spherical or oval in 
the central parts of the ganglion and flattened parallel to the surface at the 
periphery of the ganglion. (2) The distal process of the bipolar cells from the 
spinal ganglion of the guinea-pig is thinner than the proximal process. (3) The 
cells from Clarks Column are frequently essentially bipolar, 7.e., one axis cylinder 
passes upwards and another downwards, while the dendritic processes are com- 
paratively very few and insignificant. (4)-The motor cells in the spinal cord have 
winglike processes. (5) In Malapterurus the cell body appears much broken up, 
because of the great development of the dendritic processes. Fritsch’s idea of a 
‘ Bodenplatte’ from which the axis cylinder is supposed to spring is erroneous. 
This method of studying series of sections through the same cell has definitely 
shown tliat sensory, motor, and sympathetic nerve cells all possess an essential 
fibrillar structure, with chromatic granules lying between the fibrils. 
4. Cell Granulations under Normal and Abnormal Conditions, with special 
reference to the Leucocytes. By R. A. M. Bucuanan, JL.D., Liverpool. 
Classification of granules :— 
1, Normal cells with granules. 
2. Granules of ingestion. 
3. Granulation associated with the life-history of the cell. 
(a) Pigment granules. 
(6) Secretion granules, 
(ec) Abnormal granules of degeneration. 
(d) Specific granules of doubtful significance. 
Kanthack and Hardy’s classification of leucocytes was used as a foundation. 
There is considerable evidence to show that the granules of leucocytes are of 
definite formation, and analogous to secretion granules, 
They are not structural internodal points. 
In certain diseased conditions the granulation of one type of cell may so alter 
as to simulate another. 
Abnormal granulations may occur in the way of increase or decrease in amount 
or size, and histo-chemical reaction. 
Leucocytes may be classified according to the histo-chemical reactions of their 
granules into two main groups—(1) Oxyphile, and (2) Basophile. 
In the oxyphile group are included— 
(a) Finely granular oxyphile leucocytes. 
(6) Coarsely granular oxyphile leucocytes. 
(c) Myelocytes questionably. 
In the basophile group are included— 
(a) Lymphocytes : 
(6) Hyaline eeantal Leaded Siero 
(c) Finely granular basophile cells. 
(d) Coarsely granular basophile cells. 
Though definite distinctions exist in many ways between the members of each 
main group there is evidence to show that they are closely interdependent, and 
probably derivations from one definite ancestral group; the differences arising 
from environment, &c. 
