ON THE PHYSIOLOGICAL EFFECTS OF PEPTONE. 



721 



was also examined for the presence and amount of the albumose or 

 peptone excreted. 



The results, so far as ascertained at the date of this report, will be set 

 forth under the following headings : (1) Influence on the quantity of 

 urine secreted ; (2) Influence on the amount of nitrogen and of urea pro- 

 duced ; (3) Amount of peptone or albumose excreted. 



I. Influence on the Quantity of Urine. 



As will be seen in the following table, the introduction of the various 

 substances was followed by a very large increase in the amount of urine 

 secreted. The outflow reached its maximum in the second hour after the 

 injection, and then gradually declined. But even at the end of four hours 

 there was still, in the majority of cases, a decided increase, as compared 

 with the outflow prior to the injection. A few experiments showed no 

 increase. 



Table I. — Showing Quantities of Urine secreted per hour in cubic 



centimetres. 



{The injection was made at the end of the first hour, and extended over a period of 



15 to 20 minutes.) 



Exp. 



Hour 1 



Hour 2 



Hour 8 Hour 4 Hour 5 



Weight 

 of Dog 

 in kilos. 



Quantity of 



Fluid 



injected 



I. 



II. 



XXII. 

 XXVII. 



13-5 

 13 



III. 



V. 



VI. 



XXIX. 



1898. 



I. — Witte't Peptone. 



5-5 1 

 14-5 



60 



77 



70 



1102 

 124-5 



53 

 56 



29 

 36 



II. Proto-albuvwse. 



{40m. 

 \ 20m. 



30m. 



15m. 



15m. 

 { 30m. 

 \30m. 



' 45m. 

 15m. 



33-5\ 



24 \m 



25-5 ] 



9-73 r 



25 



III. Hetero-albuviost. 



33 

 20 



I 53 

 IV. Beutero-albumose, 



27-5 

 15-0 

 22-75 



V. AnipJio-pe2>tone. 



45 I 

 7-3 ! 

 3-75 



f 40m. 

 \ 20m. 



11-8 I SOc.c. 

 14-5 I 50 „ 



50 „ 

 50 „ 



50 „ 

 45 „ 



20 „ KoH. 2% 

 20 „ NaOH. 2% 



50 „ 



50 „ 

 24 „ 



50 „ 

 40 „ 



30 „ 



.S A 



