400 



CRILE— PHYSICAL STATE OF 



[April i8, 



vidual will never again be restored to his original powers after suf- 

 fering from a prolonged hemorrhage. 



Drugs. — According to their effect upon the brain cells, drugs may 

 be divided into three classes : First, those that stimulate brain cells 

 to increased activity, — as strychnine ; second, those that chemically 







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Fig. 2. Area from cerebellum, rabbit, during fright. 











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Fig. 3. Area from cerebellum, rabbit, 6 hours after fright. 



destroy the brain cells, — as alcohol and iodoform; third, those that 

 suspend the functions of the cells without damaging them, — as 

 nitrous oxide, ether, morphia. Our experiments showed that brain 

 cell changes induced by drugs of the first class are precisely the same 

 as the cycle of changes produced by the emotions and physical 



