46 



A. S. PEARSE. 



Table I. 



Showing the Effects of Injecting Certain Substances into the Body 

 Cavity of Thyone briareus (Leseur). 



Acetic acid 



Alcohol, ethyl 



Atropine 



Chloretone 



Chloroform 



Codene sulphate 



Clove oil 



Curare 



Ether 



Magnesium chloride. 

 Magnesium sulphate. 



Methylene blue 



Morphine sulphate.. 



Nicotine 



Sodium chloride 



Strychnine 



Sugar 



Turpentine 



Water, distilled 



Total 



95% 

 ? 



Sat. sol. 

 Cone. 



1% 



Cone. 



Powder 



Cone. 



20% 



20% 



2% 



1% 



•05 % 



10% 



Powder 

 50% 

 Cone. 

 Cone. 



.I-.25 



.77-3-85 



? 



■77-3-8S 



.77-3.85 



1-2 



.1-2 



? 



.77-3.85 



.77-3-85 



.77-3.85 



.77-1.54 



•5 



.15-3.85 



1.55 

 ? 



.77-3.85 



•77 

 5 



20 

 6 



2 

 10 



20 



ID 



18 

 II 



97 



the general activity without causing the reactions to become 

 abnormal. The tube-feet over the whole body were waved 

 actively back and forth, and both the peristaltic contractions of 

 the body-wall and the respiratory movements were strong and 

 frequent. Methylene blue, on the other hand, caused a complete 

 cessation of such normal activities as respiratory movements and 

 peristaltic waves ; the body-wall and tube-feet were strongly con- 

 tracted. This substance caused death in every instance. 



Autotomy took place under quite diverse conditions in the two 

 cases and cannot, in the light of these experiments, be affirmed 

 to result from either " over " stimulation or extraordinary activity 

 alone. In my opinion it may better be ascribed to what we may 

 call a " structural accident," and it may occur when any combi- 



1 From June 22 to July 5, 1909, many individuals were ejecting eggs or sperms 

 from the genital papilla. During this process the tentacles were extended and these 

 reactions in the table may have been due to the physiological condition of the indi- 

 viduals rather than the effects of the substances injected. 



