1885.] 



have 



But as I have previously pointed out CN . OH represents living, 

 CO . NH dead nitrogen; the formula therefore becomes 



= HN = C | N CH _ CH ^ _ CQ NH _ 



(NH - CO 

 = NH = C \ | 



(N.CH 3 -CH 2 



The ordinary formula for creatinine*. - 



The change is perhaps more intelligible if we consider the 

 formation of creatine. If before the separation of the molecule 

 CN . NH 2 we hydrate the compound, we have 



(OH (NH. 



CHj CH 2 ' 



cn.nh 2 + h 2 0= cn.nh 

 ch 2 ch 2 { 



(CN (COOH 



CH 2 - NH 2 



= CN . NH + | 



CH 2 - COOH 



HN CH 2 - NH„ 



+ I 

 HN CH 2 -COOH 



NH. 

 = NH = C<' 



NH . CH„ - CH„ - COOH 



NH„ 

 = NH = C / 



v N . CH 3 - CH 2 - COOH 



* Fownes, p. 614. 

 VOL. V. PT. IV. 19 



