606 REPORT—1899. 
(e) Antipeptone possesses no power of depressing vaso-mobility con- 
sistently with its lack of influence in lowering blood-pressure. 
Section IV. Local Vascular Influences. 
In this section, in addition to completing the observations on the 
limb, kidney, and spleen districts, the research was extended during the 
year so as to include the vessels of two other regions, namely, those of the 
intestine and liver. The following is a brief summary of the results as a 
whole. 
1. Intestinal Vessels. 
(a) Direct observation and record verify the inference that dilatation 
of the intestinal vessels accompanies and must to a certain extent account 
for the fall of blood-pressure preduced by injection of Witte’s ‘peptone’ 
and similar products into the vascular system. 
(6) It also establishes beyond doubt that the dilatation of intestinal 
vessels is produced by peripheral depression, or even temporary abolition 
of vaso-mobility, in the area in question. 
(c) That the order of potency in regard to effect on intestinal vessels 
corresponds with that above given for the splanchnic area in general; 
the primary proteoses exerting much the most profound influence, that of 
deuteroproteose and purified peptone being comparatively small. 
2. Renal Vessels. 
(a) The blood-vessels of the kidney do not share in the dilatation 
brought about by these substances. On the contrary, the vessels of this 
organ are much less distended under their influence than under ordinary 
circumstances. 
(b) Vaso-mobility in the renal area is much less profoundly influenced 
than in the intestinal district. 
(c) Bearing in mind the statement made in the foregoing paragraph, 
the primary proteoses are also the most effective on renal vessels. Indeed, 
they may be said to be the only members of the group which appreciably 
reduce renal vaso-mobility. 
3. Splenic Vessels, 
(a) The vessels of this district share to a moderate extent in the dila- 
tation which follows an injection of ‘peptone’ or of one of the proteoses. - 
(6) Vaso-mobility is also diminished in the splenic district, but to a 
less degree than in the intestinal. In this respect the vessels of the 
spleen take a position intermediate between those of the kidney and the 
intestine. 
(c) Proto- and heteroproteose are here also the most effective of the 
substances examined. Deuteroproteose and purified peptone have com- 
paratively little influence. 
4, Liver Vessels. 
(a) The vessels of this district suffer an enormous dilatation under the 
influence of ‘peptone’ and proteoses, corresponding to the period of 
general fall of blood-pressure. 
_ (6) This dilatation is primarily due to an increased onflow of blood 
from the vessels of the portal system, and not to mere stoppage from sup- 
posed weakening of the heart. 
(c) Under conditions of great fall of blood-pressure resulting from 
