TRANSACTIONS OF SECTION I. 897 
4. On the Effects of Successive Stimulation of the Visceromotor and 
Vasomotor Nerves of the Intestine. By J. L. Buncu, D.Sc., MD. 
When the contractions of the circular and longitudinal coats of the same 
segment of small intestine are recorded together, stimulation either of the vagus 
or of the splanchnic produces the same effect on both coats, but when the con- 
tractions of two different segments are recorded, the circular coat of one and the 
longitudinal coat of the other, the result of stimulation is not necessarily the same 
on both. Successive stimulation of the vagus and splanchnic nerves with the 
same strength of current shows some differences according to the order in which 
the two nerves are stimulated. Though the effect produced by a preliminary 
stimulation of the splanchnic can be modified or even overcome by subsequent 
excitation of the vagus, when such excitation normally gives rise to an effect 
opposed to that brought about by the splanchnic, a reversal of the order of 
stimulation does not give rise to a similar result, and a secondary stimulation of 
the splanchnic cannot, as a rule, equally modify the effect produced by preliminary 
vagus excitation. 
The vasomotor effects which Francois Franck and Hallion have ascribed to the 
vagus, I have, ina somewhat prolonged series of experiments, been unable to 
confirm. 
5. On Stimulation and Hacitability of the Anemic Brain. By Wiu11aM 
J. Gres. [Lrom the Physiological Institute of the University of 
Bern. | 
The research indicated by this subject was conducted in the Physiological. 
Institute at Bern, upon the suggestion and under the constant direction of Pro- 
fessor Kronecker. Our aim was to determine definitely the sequence of events 
during perfusion of various so-called indifferent solutions through the brain, the 
data thus obtained to afford a starting-point for future research with such liquids 
as may be found to exert specific and characteristic influences. 
In this report I shall present only the briefest outline of the experiments and 
the results obtained. 
The animals employed were toads, frogs, rabbits, and dogs. 
The solutions used were various strengths of pure sodium chloride, Ringer's 
solution and Howell’s modification of it; Schiicking’s solution, both of calcium and 
sodium saccharate, and serum. 
The perfusion in the cold-blooded animals was conducted with the least possible 
pressure through the abdominal vein. All of the various solutions already 
enumerated, except the serum, were used. We made thirteen experiments (seven 
with toads and six with frogs), each of which continued for a period of two to 
eight hours, with a total transfusate of 250 to 1,600 c.c. 
During the period of perfusion the following functions gradually weakened and 
then usually disappeared in this order: (#) Respiration; (0) Skin reflex; (c) Lid 
reflex ; (d) Nose reflex; (e) Heart beat. 
The time of disappearances of these functions varied with the total length of 
the experiments, and apparently also with the amount of fluid transfused. 
Convulsive extension of the limbs occurred in all of the experiments in the 
earlier stages, but toward the close of each, and before the reflex movements of 
the eyelids ceased, no such manifestations could be induced. 
In passing it should be noted that: 
(a) All of the animals became edematous; even those in which perfusion took 
place at the lowest possible pressures and for the shortest periods. 
(b) Also, that it was impossible to entirely remove the blood corpuscles, even 
when the perfusion continued uninterruptedly for eight hours, and as much as 
1,600 c.c. of fluid had slowly passed through the body. In all cases the fluid 
flowing from the canula, and particularly that pressed from the heart and brain, 
contained quite an appreciable number of red and white corpuscles, 
1899. 3M 
