320 ELLISON A. SMITH, JR. 



about ripe with two perfect ova at opposite poles ; in each of 

 these ova the nucleus was normal and the chromatin elements 

 and network and also nucleolus perfect and beautifully distinct. 

 Unfortunately I partially destroyed this slide through a vexatious 

 accident. I obtained, however, another pair of ovaries from an- 

 other pup, and on sectioning found many follicles with two, a 

 number with three, a few with four, and one follicle with seven ova 

 in clear view. As far as I can ascertain this is the greatest number 

 of ova recorded from any mammalian follicle. The case is es- 

 pecially interesting on account of the family history. The mother 

 setter has never had another litter. One of her daughters littered 

 in July, 1907, having nine pups, three dogs and six sluts, with 

 eight tits in lactation. 



These facts are interesting in their suggestiveness along hered- 

 ity lines, and also as to the relation between multiple ova in 

 follicles, and large number of offspring. 



The micro-photograph is of this follicle of seven ova, x 90. 

 Virginia Polytechnic Institute. 



