‘ 
164 REPORTS ON THE STATE OF SCIENCE.—1918. 
differs from all other remedies in that when it is used for the treat- 
ment of boils it is only very occasionally that fresh boils make their 
appearance during the treatment and these quickly subside without 
~ further trouble. Colloidal manganese appears to be particularly 
indicated in the treatment of staphylococcic infections. 
Turning now to the specific effects of various colloidal substances, 
it should be noted that the following are all in the sol state and 
that they must (for reasons previously indicated) have been suitably — 
stabilised. 
All these colloidal sols are thin fluids containing the colloid in so 
finely suspended a condition that it passes readily through a filter. 
Colloidal silver containing 0°05 per cent. of the metal in a colloidal 
form and not asa salt, isa clear, cherry-red liquid which has been 
used by C. E. A. McLeod with marked success in the following 
cases :— 
By local application on septic and follicular tonsilitis ; Vincent’s 
angina; phlyctenular conjunctivitis; gonorrhceal conjunctivitis ; 
spring catarrh ; impetigo contagiosus, acne of faceand body ; septic 
ulcers of legs; ringworm on body; tinea versicolor; soft sores ; 
suppurative appendicitis after operation (the wounds cleaned rapidly) ; 
pustular eczema of scalp and pubes ; chronic eczema of meatus of ear 
with recurrent boils and also chronic eczema of anterior nares; 
offensive discharge in case of chronic suppuration in otitis media ; 
bromidrosis of feet and axille ; blind boils on neck. By injection : 
gonorrhoea and chronic cystitis (local), boils, epididymitis. It has 
also been injected intravenously in general blood infections, pneu- 
monia, bronchitis and phthisis in doses of 15-45 minims, with 
marked success. 
Sir James Cantlie has found it particularly effective in cases of 
sprue, dysentery, and intestinal troubles. The dose can be increased 
from one to two or more drachms twice or thrice daily without 
danger. 
A. Legge Roe regards stable colloidal siiver as a most useful 
preparation'® in ophthalmic practice and particularly in cases of 
gonorrheal ophthalmia, purulent ophthalmia of infants, infected 
ulcers of the cornea and hypopyon ulcer (tapping of the interior 
chamber and cautery and other operative procedures being now 
rarely required, whilst if perforation does occur it is smaller and 
more manageable), interstitial keratitis, blepharitis, dacryocystitis and 
burns and other wounds of the cornea. 
T. H. Sanderson-Wells used it successfully intravenously in a 
case of!” puerperal septicemia, without any irritation of the kidneys 
and with no pigmentation of the skin. This physician has found 
that a series of intravenous injections each of collosol argentum 
every 48 hours produces no untoward effects and that recovery is 
rapid. 
Sir Malcolm Morris has found that colloidal silver is free from 
the drawbacks of other preparations of silver, viz., the pain caused 
16 Brit. Med. Journ., Jan. 16, 1915. 
7 Lancet, Feb. 16, 1918. 
