ON ANTI-SERA—COST OF CYCLING, ETC. 267 
requested that any unexpended balance may be retained to defray the cost of the 
continued experiments. 
It is proposed to publish a fuller account of the experiments with full details in 
some publication not yet decided upon. 
The experiments have been carried out in the Physiological Department of the 
London Hospital Medical College, by the kind permission of Prof. Roaf, the head of 
that Department. I desire to thank Prof. Roaf very cordially for his sympathetic 
interest in the work, and for giving me all possible facilities. 
Cost of Cycling at Varied Rate and Work.—Report of Committee 
(Professor J.S. MacponaLp, Chairman; Dr. F. A. Durriep, Secretary). 
(Drawn up by the Secretary.) 
In last year’s Report on the ‘ cost of cycling with varied rate and work,’ a graph was 
published of the data obtained fron two persons performing mechanical work upon a 
stationary bicycle against a measured and variable brake. The abscissa represented 
the metabolic expenditure and the ordinates the external work done at the various 
levels, z.e. 0, °5, 1:0, 1-5, and 2-0 kalories per minute. The experimental points lay 
practically on astraightline as long as the rate remained the same ; but as three different 
rates were employed three lines were obtained for each subject. The relative 
position of the lines and their different slope in the two cases was such as to justify 
the statement that whereas the cost of mere movement was greater for the heavier 
subject, the cost of work done was actually less, and thus the efficiency of the heavier 
subject was greater. 
At the end of the Report a third subject was referred to, though not by name ; 
Prebble, whose results, although his body weight was only 46-7 kgm., were intermediate 
between those of McHugh and Harrison. We have therefore still to deal with the 
exceptional character of these data, and hope to obtain a further set of experiments 
from this individual, since this peculiarity makes the results’specially interesting. 
During the present year work has been done on another person, Wilson, also of 
light weight (45°5 kgm. stripped). The results from this man are of lower total meta- 
bolic cost than those of McHugh and_Harrison. | For the purposes_of,comparison these 
are given here in graph form. 
CHart I. 
BRAKE POWER IN KALS. p.m. 
is) | 2 < 4 5 6 7 8 9 10 12 
METABOLISM IN KALS. p.m. x 
The experiments on Wilson were performed in precisely the same way as those of 
the other two, except that each point on the graph is the mean of three determinations 
in Wilson’s case taken at intervals of 18, 23, and 28 minutes after the commencement 
of the cycling ; whereas in the other two sets of experiments only one determination 
was made, and that at 18 minutes after the start. The labour in carrying out 
this research has consequently been increased ; but the adoption of this procedure 
