Mr Mills and Miss Bain, On the optically active, etc. 203 
On the optically active semicarbazone and benzoylphenylhydra- 
zone of cyclo-hexanone-4-carboxylic acid. By W. H. MILts, M.A., 
and Miss A. M. Barn. 
| [Read 24 February 1913.] 
THE semicarbazone of cyclo-hexanone-4-carboxylic acid can be 
obtained in an optically active form by crystallising its morphine 
‘salt from dilute alcohol, the highest value obtained for the 
‘molecular rotation in alkaline solution being [J/], 388°. The 
-benzoylpheny!hydrazone of the acid can similarly be obtained in 
an optically active form by crystallisation of its quinine salt from 
aqueous alcohol, the highest value found for the molecular rotation 
in alkaline solution being [/], 238°6°. 
These optically active compounds agree so closely in their 
behaviour with the optically active oxime of this acid previously 
described by the authors that there can be little doubt that the 
optical activity is due to similar causes in the three cases. 
The observations accordingly lend great support to the view 
that stereoisomerism in the sense of the Hautzsch-Werner hypo- 
thesis exists in the case of semicarbazones and phenylhydrazones. 
