introduced into Vertebrates 49 
| 
| 
2. If such flagellates be inoculated intraperitoneally or are 
fed by the mouth in food, the flagellates can find their way into 
the blood stream and internal organs (e.g. liver, spleen, bone- 
marrow) of the vertebrate host. 
_ 3. The insect flagellates are pathogenic to the vertebrates 
experimented upon, producing symptoms like those of leishmaniasis 
(Kala-azar). 
4, The oval post-flagellate forms appear to be more capable 
‘of developing in vertebrate hosts than are other stages of the 
herpetomonad parasite of the insect. 
| 5. . It may be expected that the various leishmaniases, occur- 
ring in different parts of the world, will prove to be insect-borne 
herpetomoniases. 
REFERENCES. 
‘Fayruay, H. B. (1911). “The Life-History of Zrypanosoma gam- 
biense and 7. rhodesiense as seen in rats and Guinea-pigs.” Proc. 
Roy. Soc., B, uxxxi1, pp. 212—227, 1 Plate. 
‘Fantuam, H. B. (1912). “ Herpetomonas pediculr, nov. spec., parasitic 
| in the Alimentary Tract of Pediculus vestumenti, the Human Body 
Louse.” Proc. Roy. Soc., B, uxxxiv, pp. 505—517, 1 Plate. 
‘Fanraayy, 1: Ba @ 0) Some Insect Flagellates and the Problem 
of the Transmission of Leishmania.” Ba Med. Journ. 11, Nov. 2 
pp. 1196—1197. 
‘Francum1, G. (1913). ‘Un nouveau protozoaire parasite de Phomme 
provenant du Brésil.”” Bull. Soc. Path. Exot., v1, pp. 156—158. 
|Prancum, G. (1913). “Nouvelle contribution a l’étude de Haemo- 
eystozoon brasiliense.” Bull. Soc. Path. Exot., v1, pp. 333—336. 
‘Laveray, A., et Francuini, G. (1913). “Infections expérimentales 
de la souris par Herpetomonas ctenocephalr.” C. Rk. Acad. Scv., 
Paris, t. 157, pp. 423—426. 
Laveran, A., et FRANCHINI, G. (1913). “Infections expérimentales 
de Mammifres par des Flagellés du tube digestif de Ctenocephalus 
canis et d’ Anopheles maculipennis.” CO. Rk. Acad. Sci., Paris, 
| t. 157, pp. 744—747. 
“Laveray, be et Francuini, G. (1914). “Infection naturelle du 
rat et de la souris au moyen de puces de rat parasitées par 
. Herpetomonas pattoni.” C. R. Acad. Sci., Paris, t. 158, pp. 450 
—453. 
Laveran, A., et Francutni, G. (1914). ‘Infection de la souris au 
moyen des flagellés de la puce du rat, par la voie digestive.” C.F. 
i Acad. Sci., Paris, t. 158, pp. 770—772. 
| Laveray, A., et FRaNCHINI, G. (ome): “Infections de Mammiferes 
| par des flagelleés Vinvertébrés.” Bull. Soc. Path. Exot. Vil, pp. 605 
—612, 4 figs. 
Licer, L. (1902). “Sur la structure et le mode de multiplication 
{ 
des Flagellés du genre Herpetomonas, Kent.” C. R. Acad. Sct., 
Paris, t. 134, pp. 781 —784, 7 figs. 
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