1896.] Messrs Easterfield and Wood, On Indian hemp resin. 147 



Physical constants. 



Calculated for 



C 29 H 60 Found 



Melting point = 63—64 63-5—64 



Boiling point | =28 ._ 286 285-290 



at lo mm. J 



Narcotic Red Oil, " Cannabinol," C 18 H., 4 0o. 



This forms more than 96 per cent, of fraction (c) ; it distilled 

 constantly at 265° C. (20 mm.). Analysis agreed with the formula 

 C ls H 24 0o. 



Analysis. 



Calculated for 

 Ci 8 H 24 2 Found 



C = 79-4 79-1 



H= 8-8 9-0 



The figures are the mean of four concordant analyses made 

 upon different preparations. 



The molecular weight by Raoult's freezing-point method was 

 found to be 273, the formula C 18 H, 4 0, .= 272. 



The substance is liquid above 60° C, below that temperature 

 it is a cherry-red, semi-solid resin. It is insoluble in water, but 

 dissolves easily in most organic solvents. 



The compound yields mon-acetyl and mono-benzoyl derivatives, 

 both of which can be distilled under diminished pressure ; it is 

 hence to be regarded as a hydroxy] compound ; it yields nitro 

 and apparently sulphonic derivatives and must therefore be a 

 closed chain derivative. Further experiments upon the constitution 

 of this remarkable substance are in progress. The authors propose 

 the name Cannabinol for the compound. 



Cannabinol has been isolated by the authors from all the usual 

 pharmaceutical preparations of Cannabis Indica. The experiments 

 of Mr C. R. Marshall, Assistant to the Downing Professor of 

 Medicine, shew conclusively that the narcotic action of the hemp 

 plant is to be ascribed to the presence of this compound. 



The main results arrived at in the present investigation are 

 summarised in the subjoined table : 



