Ryan—On the Synthesis of Glucosides. 517 
The anhydrous compound gave the following numbers :— 
0:1512 gave 0°3392 CO. and 0:1086 H.0, C 61:2, H 7:9. 
C,;H.O,; requires O 61:5, H 7-7 per cent. 
Carvacrylglucoside is easily soluble in alcohol or acetone, but 
less readily so in cold water or ether, and is almost insoluble in 
benzene, chloroform, or light petroleum. It does not reduce 
Fehling’s solution before, but readily after, hydrolysis by heating 
with dilute acids or emulsin. 
The behaviour of carvacrylglucoside towards dilute alkali is 
characteristic. It dissolves slowly, but completely in the alkali, 
and is reprecipitated unchanged by the addition of dilute acids or 
ammonium carbonate. Hence carvacrylglucoside contains an 
unchanged phenolic hydroxyl group. 
In conclusion, | must express my indebtedness to Mr. W. 8. 
Mills, m.a., for his assistance in the above investigation, and to 
Professor Emil Fischer, in whose laboratory in the University of 
Berlin a portion of the work was carried out. 
NOTE ADDED IN THE PRESS. 
On THE ConstITUTION oF CARVACRYLGLUCOSIDE. 
Since the above paper was read before this Society two 
important papers by Emil Fischer and Armstrong, and by 
Koenigs and Knorr, have appeared in the Chemisches Central- 
blatt, which support my formula for carvacrylglucoside. 
The constitution of the substance obviously depends entirely, 
so far as the glucose rest is concerned, on the constitution of 
acetochloroglucose or acetobromoglucose, since it has been obtained 
from both those substances by the replacement of Cl or Br atoms 
respectively by the carvacrol rest with simultaneous saponification 
of the acetyl groups. | 
Emil Fischer and Armstrong have shown that ( pentacetyl- 
glucose reacts with liquid hydrochloric acid to form (3 acetochloro- 
glucose :— 
CH,0Ac - CHOAc : CH - (CHOAc), - CHOAc + HCl 
| O | 
= CH,0Ac: CHOAc . CH - (CHOAc), . CHCl1+ CH,COOH. 
| O | 
SCIENT. PROC. R.D.S., VOL. IX., PART IV. 2P 
