54 JYarcoti7ie, and Sulphate of Morphine. 



now, after having taken this dose for a great number of times, for the 

 relief of an habitual Dyspnoeal cough, it seems to "be full as much as 

 I can bear, without the production of disagreeable symptoms. The 

 first two or three doses that I ever took in the evening, caused a head- 

 ache, for some hours, the next morning. Mrs. M T , for 



pain in the stomach, took one fourth of a grain of Pelletier's Sulphate 

 of Morphine, with rehef of the pain, for which it was prescribed, 

 within ten minutes. In about three hours, it caused so much vertigo, 

 faintness, and nausea, as to confine her to the bed, for the remainder 

 of the day, which was seven or eight hours. A night's sleep, as is 

 usual, entirely removed these symptoms. Miss M — A — M — , of 

 an exquisitely nervous and susceptible temperament, took, at bed- 

 time, for irritation in the alvine canal, one eighth of a grain of Pel- 

 letier's Sulphate of Morphine, made into a pill with extract of Gen- 

 tian, and the same quantity the next morning, before rising. For 

 the whole day, she had very troublesome vertigo, faintness, and 

 nausea, and also frequent retching, which symptoms did not leave 

 her, till after another night's sleep ; and even the day following, she 

 had very great languor and lassitude. H — R — P — , a young lady 

 aged 14, on account of a Diarrhoea, took, at 10 o'clock A. M. one 

 fourth of a grain of Sulphate of Morphine, made into a pill with ex- 

 tract of Gentian, which entirely suspended the Diarrhoea, so that there 

 was even no threatening of a return. Between one and two o'clock 

 P. M. she began to complain of vertigo, epigastric uneasiness, and 

 nausea, which, in a short time, in consequence of some exertion and 

 motion, produced vomiting. After this, the vertigo, epigastric un- 

 easiness, and nausea, increased considerably, and were attended with 

 a distressing faintness, which soon confined her to the bed, where 

 she was obliged to remain, the whole afternoon. About 6 o'clock 

 P. M. she got up, which increased all the disagreeable symptoms, 

 and again produced vomiting. She again went to bed, had cool skin 

 and irregular pulse, and about seven o'clock, even whilst upon the 

 bed, had another paroxysm of vomiting. After this, she got up, 

 merely for the purpose of undressing. After a night's sleep, all disa- 

 greeable symptoms entirely disappeared, and the next day, she was 

 as well as usual. Dr. S — F — , for pain and distress in the stom- 

 ach, connected with long protracted functional derangement of the 

 digestive organs, took one fourth of a grain of Sulphate of Morphine, 

 which gave perfect relief, in a very few moments, but, in two or three 

 hours, occasioned vertigo, faintness, and nausea. Dr. Baxter, one 

 of the translators of Magendie's Formulary, says, " I have lately 



