April 23, 1920] 



SCIENCE 



413 



with the War Demonstration Hospital, New 

 York City. The assistance was not limited 

 to the active period of the war, but continued 

 after the signing of the armistice. 



The eighteenth annual meeting of the North 

 Carolina Academy of Science will be held on 

 April 30 and May 1, at the N. C. State College, 

 West Ealeigh. Professors A. H. Patterson, 

 physicist, and E. W. Leiby, entomologist, 

 are president and secretary-treasurer, respec- 

 tively. 



UNIVERSITY AND EDUCATIONAL 

 NEWS 



The family of Henry Phipps have given 

 $500,000 to the Henry Phipps Institute of the 

 University of Pennsylvania for the study of 

 tuberculosis. 



Mr. James F. Brady and Mr. Vincent Astor 

 have subscribed $250,000 to the two million 

 dollar endowment fund of the New York Post 

 Graduate Medical School as soon as the first 

 million dollars has been raised. 



Dr. Albert W. Smith, dean of the college 

 of mechanical engineering of Cornell Univer- 

 sity, has been appointed acting president of 

 the university during President Sehurman's 

 leave of absence. President Schunnan will 

 resume office on June 1, retiring on June 2.3. 



Mr. Albert E. White, formerly head of the 

 metallurgical branch, technical stafi of the 

 Ordnance Department, has returned to his 

 former position as professor of chemical engi- 

 neering at the University of Michigan, Ann 

 Arbor, Mich. 



Dr. William Leonidas Burlison, professor 

 of crop production of the University of Illi- 

 nois, has been appointed head of the depart- 

 ment of agronomy, to fill the vacancy caused 

 by the death of Dr. Cyril Gr. Hopkins. 



DISCUSSION AND CORRESPONDENCE 



CEREBELLAR LOCALIZATION BY THE 

 APPLICATION OF STRYCHNINE 



There exists, at the present time, a con- 

 siderable diversity of opinion with respect to 

 the localization of functions in the cere- 

 bellum. The conception of cerebellar local- 



ization is based on the studies of Elliot 

 Smith, Bolk, van Eynberk, Andre- Thomas 

 and Barany. Nevertheless, in a recent study 

 of war woimds involving the cerebellum, 

 Gordon Holmes was unable to find definite 

 evidence in support of the localization 

 doctrine. 



The present writer is conducting a series 

 of experiments in which an effort is being 

 made to solve the problem by the application 

 of strychnine to the cerebellar cortex. The 

 experiments are being jierformed on cats 

 anesthetized with chloroform and ether. Tra- 

 cheotomy is carried out and both carotid 

 arteries are ligated. The left cerebellar hem- 

 ispere is then exposed. A 1 per cent, solution 

 of strychnine nitrate containing methylene 

 blue is applied to the surface with a small 

 pledget of absorbent cotton. Any excess is 

 carefully wiped off and spreading to the 

 medulla oblongata is precluded by the use of 

 thick vaseline. The area covered by the 

 strychnine solution apparently embraces the 

 " crus secundum " and to some extent the 

 " crus primum " of Bolk. The crus secundum, 

 according to van Eynberk, is concerned with 

 the ipsilateral hind limb, whilst the crus 

 primum is concerned with the ipsilateral 

 forelimb. 



After applying the strychnine the animal is 

 laid on its back and the narcosis is allowed 

 to subside slightly. Within about 5 minutes 

 it is found that flexion applied to the 

 ipsilateral (left) hind leg at ankle, knee and 

 hip evokes a succession of regular tremors 

 which may persist for an indefinite period. 

 Mechanical stimxdation or faradization of the 

 pads of the foot yields a like result, which is 

 also evokable by induction of the knee-jerk. 

 Frequently the leg is carried by the rhyth- 

 mical tremors into a condition of sustained 

 extension, which recalls vividly the condition 

 met with in " decerebrate rigidity." 



Application of the above-mentioned modes 

 of stimulation to the contralateral (right) 

 hind leg is usually without result but at times 

 phenomena of similar kind are induced. 

 These, however, are weaker and of shorter 

 duration than in the ipsilateral limb. It ap- 



