1919.] The Siath Indian Science Congress. Ixxxi 
followed by fatal recurrence of the terrible drain of fluid from 
the system. At the time I commenced my investigations the 
method was seldom used, as shown by the fact that a search 
tal from 1895 to 1904 showed no case in which large saline 
87:4 per cent. Indeed it was generally recognized that once 
an European patient reached the collapse stage in cholera 
recovery scarcely ever took place 
Recent RESEARCHES ON THE TREATMENT OF CHOLERA. 
s the first whole-time professor of pathology in Bengal, 
the ita of cholera, who stuck to unlucrative research work 
for any length of time, this fell disease naturally attracted my 
attention, but it was not until after the completion of the first 
edition of my work on Fevers in the tropics, the collection ‘of 
material for which occupied me for twelve years, that I was able 
take up serious work on cholera in 1908. I had ou ae 
made a number of blood counts and, with the help of m 
friend Major Megaw, I.M.S., had studied in 1906 Latta aiid 
Mackintosh’s plan of injecting large amounts of normal or 
isotonic salt solutions, that is one peer 3 the same pro- 
while to try a stronger salt solution, a on return from 
190 
last three periods of furlough I discovered respectively the 
development of the Gagatlace stage of the Leishman-Donovan 
body, furnishing an important t clue to the probable mode of 
infection. of kala-azar, the hypertonic saline treatment of 
exacting labours. Up to this time the strength of salines 
generally advised in cholera was 0°6 per cent, although recent 
