1919.] The Sixth Indian Science Congress. eexiii 
that the British Spite ed from beri-beri, a disease from which the Indians 
were iigares makes a comparison of their diets of peculiar i ea oy itis 
Troops ate horse ee ; ~ Pe idians did not. Indian Troops 
ish 
f 
e the absen 
diet of British ba os led to reduction in body Eakeny sepa ed tem 
ture, slowing of the pulse ee marked de bility. 
The vitamine theory of beri-beri is rata a and the investigations 
carried out at beat Lister “Tnatituts y Miss Chick and Miss Hume are 
referred to in some detail and the eaniae. subscribes to the conclusion 
reached by Miss faiecgs and Miss Hume that the British Troops were 
protected sien vy by the ample em gs fick meat or horse flesh and that 
the India ealdiers, though protected beri-beri by the nature 
of their corel ration, failed to prees a fin a ate of anti-scorbutic 
vitamine owing to their refusal to eat fresh meat. 
The rations issued to British and tiated Troops during the three 
stages of the siege are detailed in an appendix to the paper. 
Quinine in the treatment of malaria—what is known and 
what is not known about quinine.— By J. W. ConnwaLv. 
_ We are not yet in possession of complete sahil’ ge of the action 
immediate and remote, of the majority of t ney drags which are freely 
that it de 
by so ie ie in pee sls with the proper oxygenation of the t d 
ngs heat production ; bl it esi all cellular enzymes, and 
so lessens the — supply os hormo and checks digestion and 
sentcaiftatiein's that it de epresses the “circulatory and respiratory m echan- 
isms, and that watts products t tory 
functions oe in partial char degre In robust health the a entaaae nd 
compensator ay nigeae’ f the tissues enable an individual to withstand 
a dosage which i eee state would be more than his weakened 
organs could dea Lw it 
In the tre recta ‘ot malaria the non-selective, toxic effect of quinine 
has been Bevel ca y ignored. 
Too much atten — has been paid in India to relatively unimportant 
sulsinlenibel side issues and too little to co-ordinated scientific inquiry 
into ~ oP athology o et abana nd the p hnemacology of quinine 
following matters call for investigatio 
ay Whether quinine in harmless doses can act as a rebable prophy- 
t Br uld cease. 
(2) Whether malari n be cured by doses of quinine which, 
pared with the harmfal Pub dot of ‘te parasite, are pareve 
harmless to the patien 
(3) Whether any usefu i purpose is served by dosing a patient with 
(4) Whether any other Aaa ig be found weer will sonra! the 
genet i — without at the same time serio harm 
ing the t : 
(5) oe what Fe dhaieie changes are caused by the malarial 
parasite 
