242 DR. W. N. F. WOODLAND ON THE 



products of active tissues which act as reducing agents and so 

 facilitate the abstraction of the oxygen dissolved in the plasma. 



• (3) I have adduced the striped darkening of the cytoplasm of 

 the gas gland cells bordering the capillaries as evidence of the 

 absorption of dissolved oxyhajmoglobin from the blood and that 

 this is evidence of absorption is undoubted, but that it is absorp- 

 tion of oxyhgemoglobin is of course only an inference from the 

 hiemolycis of the blood corpuscles, the production of oxygen gas 

 by the gland cells and other considerations. I wish to state 

 here, previous to sending away the final proofs of this paper, that, 

 judging from preliminary experiments with the Israel- Pappen- 

 heim stain for hfemoglobin, kindly recommended to me by 

 Dr. G. A. Buckmaster, I have been able to detect the actual 

 presence of hsemoglobin in the cells of the active gas gland and 

 its passage thereto from the blood stream, and Dr. Buckmaster 

 has confirmed these preliminary observations of mine. I intend 

 to repeat these observations on an extended scale on fresh 

 material shortly, and until I have done so I do not wish the 

 above statement to be considered as final. 



References to Pancreas Literature (pp. 198, 200 in text). 



1 Dale, H. H. — " On tlie Islets of Langerlians in the Pancreas." Phil. Trans. 

 Roy. Soc. Lond., VoL cxcvii, 1905, pp. 25-46. 



2. DE Witt, L. M. — " The Morphology and Physiology of Areas of Langerhans in 



some Vertebrates." Jour. Exper. Med. New York, Vol. viii, 1906, 

 pp. 193-239. 



3. DiAMAEE, V. — " Studii comparativi suUe isole di Langerhans de pancreas." 



Intern. Monatsschr. f. Anat. u. Physiol. Leipzig, Bd. xvi, 1899, 

 pp. 165-209. 

 3 a. Flint, M. — " Das Bindgewebe der Speicheldriisen nnd der Pankreas, etc." 

 Arch. f. Anat. u. Entwick. Leipzig, Jahrg. 1903, pp. 61-106. 



4. Laguessb, E. — " Developpement du Pancreas cbez les Poissons Ossenx." 



Comptes reiidus hebdoni. des Seances et Memoires de la Soc. dc 

 Biologie, Ser. 9, T. i, 1889, p. 341. 



5. " Pancreas intra-hepatique cliez les Poissons." Op. cit., Ser. 9, T. iii, 



1891, p. 145. 

 6 " Sur la Formation des ilotsde Langerhans dans le Pancreas." Op. cit., 



Ser. 9, T. v, 1893, pp. 819, 820. 

 rj " Developpement du Pancr(5as chez les Poissons Osseux." Journal 



de I'Anatomie et Physiologie, Paris, T. xxx, 1894, p. 79. 

 g " Structure et Developpement du Pancreas d'apres les travaux recents." 



Ibid. pp. 591-608. 

 g_ . " Sur le Pancreas du Crenilabi'e et particuli^rement sur le Pancreas 



intrahepatique." Kevue Biologique du Nord de la France, T. vii, 



1891-1895, pp. 343-360. 

 \Q_ "Sur la Structure du Pancreas chez quelques Ophidiens et particuli- 



erement sur les tlots endocriues." Arch. d'Anat. Micr. Paris, T. iv, 



1901, pp. 157-218. 

 11 Lane M. A. — " The Cytological Characters of the Areas of Langerhans." 



Amer. Journ. Anat., Vol. vii, Part 3, 1908, pp. 409-421. 

 12. Leavaschew, S. — " Ueber eine eigentiimliche Verandernng der Pankreaszellen 



warmbliiliger Tiere bei starker Absonderungsthatigkeit der Driise." 



Arch. f. Mikr. Anat., Bd. xxvi, 1886, pp. 453-485. 

 ■ 13 Massaei. — " Sul pancreas di pesci." Eend. K. Accad. dei Lincei, Vol. vii, 



Fasc. 5, 1898, pp. 134-137. 

 14. Opie, E. L. — " Disease of the Pancreas." (Lippincott) Philadelphia, 1903. 

 1Q . " The Histology of the Islands of Langerhans." Johns Hopkins 



Bull., Baltimore, Vol. vi, p. 117. 



16 Oppel, a. — ' Lehrbuch der Vergleich. Mikr. Anat. Wirbeltiere.' Jena, Bd. iii, 



1900, pp. 800-818. 



17 Rennie J. — " The Epithelial Islets of the Pancreas in Teleostei." Quart. 



Jour. Micros. Science, Vol. xlviii, 1904-1905, p. 379. 



