472 



SCIENCE 



[N. S. Vol. XXVI. No. 667 



effect of rabbit serum on various positive aud 

 negative colloids, Field found that such serum 

 precipitated colloidal platinum and colloidal 

 silver to a fair degree. Serum from one 

 rabbit precipitated colloidal platinum com- 

 pletely at 1-100, slightly at 1-200 and not at 

 all at 1-500. This serum precipitated col- 

 loidal silver completely at 1-10, partially at 

 1-100 and not at all at 1-250. After receiv- 

 ing three injections of colloidal platinum in 

 three weeks this rabbit's serum then precipi- 

 tated colloidal platinum completely at 1-1,000, 

 slightly at 1-1,250 and not at all at 1-1,500, 

 whereas it precipitated colloidal silver com- 

 pletely at 1-100, slightly at 1-250 and not at 

 all at 1-500. 



Serum from another rabbit originally pre- 

 cipitated colloidal platinum completely at 

 1-50, partially at. 1-100 and not at all at 

 1-250. The same figures held good for col- 

 loidal silver. After three injections of col- 

 loidal silver during three weeks, this rabbit's 

 serum precipitated the colloidal silver com- 

 pletely at 1-500, partially at 1-1,000, and not 

 at all at 1-1,250, whereas colloidal platinum 

 was completely precipitated at 1-200, partially 

 at 1-500 and not at all at 1-1,000. 



In other words the precipitating power of 

 the serum of the first rabbit, after it received 

 three injections of the colloidal platinum, had 

 increased from 1-100 to 1-1,000 {=^ ten times), 

 whereas for the colloidal silver there was only 

 a very slight increase. Serum from the 

 second rabbit, which received colloidal silver, 

 increased its precipitating power from 1-100 

 to 1-500, whereas for the colloidal platinum, 

 from 1-100 to 1-250. In both these rabbits 

 there was then an increase in the precipitating 

 power of the serum after injection of these 

 coUoidaSl metals, and it would seem that they 

 increased more for the metal injected than for 

 the other. 

 Remote Results of Transplantations of Blood 



Vessels: Alexis Carrel. 



The results of arterio-arterial, veno-venous 

 and arterio-venous anastomoses have remained 

 excellent for many months. No stenoses or 

 aneurisms have been observed on the arterial 

 anastomoses even six to seven months after 



operation. No stenosis occurred after venous, 

 anastomosis : a cat, in which an Eck fistula 

 was made eighteen months ago by Carrel and 

 Guthrie, is still in good health. The same is 

 true of an arterio-venous anastomosis : the 

 jugular vein and the carotid artery of a dog 

 were anastomosed by Carrel and Guthrie 

 twenty-two months ago, and now strong thrills 

 and pulsations can easily be detected by palpa- 

 tion of the jugular vein. The modifications- 

 of the vascular walls are produced mainly by 

 the changes of blood pressure. No great 

 change occurs if the blood pressure of the 

 transplanted vessel be not modified. Seg- 

 ments of carotid, aorta or vena cava of one 

 animal, transplanted in the carotid, aorta or 

 vena cava of another animal of the same size 

 and species, do not undergo any important 

 anatomical modification. If blood pressure is 

 diminished, the wall of the transplanted vessel 

 becomes thinner. Six months after the opera- 

 tion, it was found that the wall of the carotid 

 transplanted in the external jugular vein was- 

 thinner than the normal one. If blood pres- 

 sure is increased, hypertrophy of the wall 

 ensues. A segment of external jugular vein 

 interposed between the cut ends of the carotid 

 artery was a little dilated and its wall was 

 as thick as the arterial wall, eight months 

 after the operation. In other cases, there was- 

 no dilation of the lumen of the vessels. As- 

 a rule when a vein is anastomosed uniter- 

 minally to an artery, its lumen is found to be- 

 dilated, six or seven months after the opera- 

 tion. Nevertheless, after one year the lumen 

 may progressively diminish in size, as was 

 seen in a dog operated upon twenty-two 

 months ago. 



It may be concluded that transplanted 

 blood vessels adapt themselves to the pressure 

 by thinning or thickening their walls. 

 The Dependence of Gastric Secretion upon 

 the Internal Secretion of the Salivary 

 Glands: John C. Hemmeter. (Communi- 

 cated by S. J. Meltzer.) 

 The relations of the gastric secretion to the 

 salivary glands are illustrated by the follow- 

 ing clinical and experimental observations : 

 1. In four cases of Mikulicz's disease, with 



