SCIENCE 



FEroAY, March 3, 1916 



CONTENTS 



General Problems and Tendencies in Cancer 

 Besearch : De. Leo Loeb 293 



The United States Fisheries Biological Station 

 at Beaufort : Samuel F. Hildebrand 303 



Alvin Davison-: Peofessor H. D. Bailey .... 307 



Presentation of a Portrait of J. Peter Lesley. 308 



Scientific Notes and News 308 



University and Educational News , 311 



Discussion and Correspondence: — 

 The Fundamental Equation of Mechanics: 

 Peofessoe Edwaed V. Huntington. Polari- 

 zation of Globigerina: Professoe B. K. 

 Emeeson. The Teaching of the History of 

 Science: Peofessoe C. B. Ciioss 312 



Scientific BooTcs: — 

 Donisthorpe on British Ants: Peofessoe W. 

 M. Wheelee 316 



Special Articles: — 



The Importance of the Bacterium iulgar- 

 icus Group in Ensilage: O. W. Huntee and 

 L. D. Bushnell 318 



The American. Physical Society: Peofessoe 

 A. D. CtoLE 320 



The Botanical Society of America: De. H. H. 

 Baetlett 322 



Societies and Academies: — 



The Biological Society of Washington: M. 



W. Lyon, Je 329 



MSS. intended for publication and books, etc., intended for 

 review should be sent to Professor J. MoKeen Cattell, Garrison- 

 on-Hudson. N. Y. 



GENERAL PROBLEMS AND TEND- 

 ENCIES IN CANCER RESEARCHi 



Aptee the successful continuous trans- 

 plantation of rat sarcoma and mouse carci- 

 noma had shown that we possessed a 

 method suitable for the study of the biol- 

 ogy of tumors, and which promised a rich 

 harvest of results, the decade following the 

 year 1901 was to a great extent devoted to 

 the study of propagated tumors rather than 

 to the analysis of the first origin of tumors, 

 although this latter problem had never been 

 entirely neglected. "Within recent years, 

 however, much attention has been given to 

 the origin of tumors. The so-called endemic 

 occurrence of cancer which we observed in 

 the case of cattle and rats, and which cer- 

 tain investigators noted in the case of mice 

 and other animals, suggested to us sixteen 

 years ago the possible significance of hered- 

 ity as an etiological factor. Some years 

 later, observations which we made in a 

 mouse-breeding establishment in Granby 

 confirmed this hypothesis; but it is only 

 during the last six years, following the ob- 

 servations of Tyzzer and Murray, that our 

 investigations, carried out in conjunction 

 with Miss Lathrop, proved on a very broad 

 basis the very great significance of hered- 

 ity in the transmission of cancer in mice, 

 the partial independence of the age and fre- 

 quency factors, and the correlation between 

 cancer frequency and structural and func- 

 tional characteristics of the animal. The 

 results of hybridization experiments which 

 we carried out on a large scale indicate that 

 in some crosses the tendency to a high 



1 An address before Section VIII. of the II. 

 Pan-American Scientific Congress on January 5, 

 1916. 



