Ringworm Fungus. By M. Morris & G. C. Henderson. 337 



his results and ours may possibly be due to the acidity of his 

 medium. We can offer no other explanation of the great 

 differences between the three specimens which he figures. 



Atkinson's results, as shown in his first figure, exactly corre- 

 spond with our own. It is only in the latter stages we differ. 

 The large sporangium-like bodies and lateral buds, which led him 

 to assign ringworm to the Mucors, seem to correspond with the 

 terminal masses described in section H. 



In.Thin's cultivations, the swelling and budding of spores and 

 the early formation of mycelium agree with the facts previously 

 described by Grawitz and Atkinson, and now confirmed by our- 

 selves. We are inclined, however, to think the appearances which 

 he considers to be spores, are spaces in the protoplasm of the 

 mycelium, filled with highly refractile fluid, as in the longest 

 filaments, which were observed by us for some weeks, these bright 

 roundish spaces gradually enlarged and coalesced, while the proto- 

 plasm shrivelled up and disappeared. 



Kobner * believes that these so-called spores within the 

 filaments and terminal buds are only oil-globules. In using 

 vitreous humour we found, hke Thin, a very abundant develop- 

 ment of bacteria, and in proportion to their growth a coincident 

 cessation of that of the ringworm. 



Conclusions. 



We think that the experiments we have described warrant the 

 following conclusions : — 



1. That the spores of Trichophyton tonsurans grow freely on 

 the surface, and in the substance of gelatine peptone at tempera- 

 tures between 15° and 25° C. 



2. That the mycehum only will grow on the substance of the 

 jelly, and that the hyphse require air to produce conidia. 



3. That the branching, septa formation, and fructification are 

 identical with those of Penicillium. 



4. That spores of the second generation reproduce ringworm 

 on the human skin. 



5. That outgrowths resembling " resting-spores " appear on 

 some of the fllaments.f 



• Virchow's Arcliiv, xxii. (1861). 



+ "We have to express our great obligation to Dr. Maddox for the photo- 

 micrographs -which he has produced to illustrate this paper. 



The power used was a Beck l-5th, and the amplification was 1000. 



Ser. 2.— Vol. III. 



