384 UNIVERSITY OF VIRGINIA PUBLICATIONS 



The common bile duct was distended, being as large as a lead pencil. On opening 

 it a flat worm was found completely filling the duct, looped on itself with the head in 

 the lower half of the cystic duet. The rest of the cystic duct was clear. The loops of 

 the worm filled the hepatic duct, extended into several main branches of the hepatic 

 duct and for quite a distance up into the liver and also along the duct of Wirsung for 

 2 or 3 cm. into the pancreas. Loops of the worm also extended into the intestinal 

 canal. 



The liver was of about the same size as that of sheep No. 1. Surface was smooth 

 except for the adherent cyst above described, consistence moderately firm. Just to 

 the left of the median sulcus of the anterior margin was an irregular wedge with the 

 broadest surface toward the edge of the liver, measuring 6x8 cm., rough, firm, of 

 scar-like character, pale, yellowish on section and sharply marked from remainder 

 of liver. On section of liver the main branches of the bile ducts were filled with tape- 

 worms. 



Spleen measured 10 x 6 x 2 cm. It was smooth, soft, and normal on section. Kid- 

 neys were alike, the capsfile stripped off readily leaving a smooth surface. On section 

 the cortex measured about 8 mm. The glomeruli were fairly distinct, the pyramids 

 pale, the kidney apparently normal. The adrenals 2 x 1 x 0.75 cm. were bean shaped, 

 with pigment in their surfaces. On section, cortex and medulla were clearly marked, 

 uniform, and apparently normal. Pancreas was soft and friable but presented no ab- 

 normality except for the worm in the duct. Bladder was empty and contracted; the 

 mucosa pale. Aorta elastic and apparently normal. Heart. The pericardial sac 

 contained free within it a cyst like those described above. Pericardial fluid not in- 

 creased. Fat reduced. Surfaces smooth and glistening. The valves were clear and 

 delicate; Foramen ovale closed; myocardium was pale, semi-translucent and brown. 

 The lungs were alike. There was no free pleural fluid. The pleural surfaces were smooth 

 and glistening. The lungs were small, crepitant, cushiony. The bronchi and vessels 

 were clear and pale. On section, the lungs were pink and of uniform appearance ex- 

 cept for one or two small patches of emphysema. The brain and cord presented no 

 abnormality. The nares and adjacent sinuses were clear throughout. The trachea 

 and esophagus were normal. The paunch was filled with hay and grass well chewed. 

 The other stomachs were normal with the normal odor of gastric contents. In the 

 duodenum were found several heads of tape-worms apparently four in all, with a 

 great many segments. The rest of the intestine contained normal looking contents. 

 The mesenteric lymph glands were enlarged, soft, pale and apparently normal on 

 section. 



Microscopic report. Heart. Section stained well, heart muscle cells for the most 

 part were distinct though slightly granular and a number of the fibers had a wavy 

 contour. Here and there were found cysts, maybe one-half dozen altogether embedded 

 in the muscle and showing no reaction around them. The lung tissue was vesicular 

 and normal. Some of the lung vessels contained an excess of leukocytes. 



Liver. The liver cells were large, somewhat vacuolated and granular. ' The bile 

 ducts were dilated and lined with high columnar epithelium showing abundant goblet 

 cells. The surrounding tissue was slightly edematous and occasionally peculiar 

 cells and debris were found in the lumen of the bile duct, apparently desquamated- 

 epithelial cells. The lobules could be recognized fairly distinctly; the central 

 two-thirds of the lobule stained deeper than the outer third, the outer third 

 showing cells more vacuolated, paler and more granular and containing more 



