386 UNIVERSITY OF VIRGINIA PUBLICATIONS 



Muscles pale, translucent, reddish brown. Peritoneal surface smooth and glistening. 

 No excess of fluid, one parasitic cyst found in peritoneal cavity. 



Heart. Epicardial fat very slight in amount, surfaces smooth and glistening, 

 valves clear and delicate, foramen ovale closed. Myocardium translucent, reddish 

 brown. The free margin of the left aortic leaflet presented a line of pigmentation. 

 Lungs free from adhesions, pleural surfaces smooth. The color of the lungs in general 

 was pink with here and there small groups of emphysematous cells appearing gray. On 

 the surface of each lung were two or three areas from 0.25 to 1 cm. in diameter which 

 were firmer, irregular, slightly darker red than surroundings and apparently consoli- 

 dated. On section, the lung elsewhere appeared pink, the bronchi and vessels ap- 

 peared clear except for the firm dark red areas. Spleen was small, smooth, soft; 

 the structures showed well on section; condition apparently normal. Liver was 

 small, surfaces smooth, the edge moderately firm and sharp; color, brownish red, 

 semi-translucent. On section, appearance was uniform. The lobules were not dis- 

 tinct. On the convexity of right lobe of liver a pin-head sized whitish fibroid 

 nodule was met with. Kidneys appeared pale and normal but under the capsule 

 there were one or two fibroid nodules, 1 or 2 mm. in diameter embedded in the 

 cortex. Pelvis and ureters clear. Bladder empty. Mucosa pale. Ureters, tubes 

 and ovaries small and normal. Pancreas soft, friable, apparently normal. Diges- 

 tive tract contained normal food in abundance and showed no lesion. Brain and 

 cord apparently normal. No excess of fluid. No adhesions. The sinuses connected 

 with the nose were -empty and clear. There was a slight muco-purulent exudate 

 over the turbinate bones. The incisor teeth showed irregularities in position and 

 were loose, otherwise mouth was clear. Mesenteric fat and body fat in general 

 was very greafy reduced. The adrenals were bean-shaped with dark pigmentation 

 over the surface showing the cortex and medulla clearly on section. Hemolymph 

 glands were numerous, pin-head in size. 



Microscopic report. Heart. Striations and fibrillations distinct. Muscle cells 

 slightly granular, otherwise apparently normal. Two or three small sarcocysts were 

 found. In two instances the cyst occurred in a Purkinje cell. Lung apparently nor- 

 mal; section from nodule not obtained. 



Liver. The section was distinctly cloudy. The liver cells were large, frequently 

 vacuolar and granular. The bile ducts were distended, though only to a slight degree. 

 The blood in the portal vessels contained an excess of leukocytes, quite a number of 

 which were eosinophilic and in addition there was a distinct increase of lymphocytes in 

 the portal blood. The peribiliary tissue was edematous and contained a small number 

 of cells, partly lymphoid, partly eosinophilic. 



Spleen, slightly congested, otherwise normal. The kidney tubules were lined 

 by cells which were markedly vacuolated; otherwise the section was normal, except for 

 the nodule in the cortex. A section through one of the white nodules described in the 

 autopsy report showed that the nodule was embedded in the cortex of the kidney. 

 In the center of the nodule was a small focus of coagulation necrosis with fragment- 

 ing nuclei surrounded by fibroblasts and mononuclear cells, some of which were 

 lymphoid in character, others larger, and like mononuclears. These large and small 

 mononuclear cells, mingled with fibroblasts, extended quite a distance between and 

 compressed tubules. In the nodule were found three chief foci of coagulation necro- 

 sis and two or three smaller ones. The fibroblasts appeared to form a complete cap- 

 sule immediatelv around the foci of necrosis. Outside of this infiltration became much 



