LOCOWEED DISEASE OF SHEEP 419 



Microscopic report. Heart muscle cloudy, striations indistinct, fibrillations still 

 well marked. 



Lung, showed bronchopneumonia, many of the alveoli being packed with a cel- 

 lular exudate, while adjacent alveoli were relatively free or showed only coagulated 

 albumin and desquamated epithelium. The exudate consisted of desquamated epi- 

 thelium, coagulated albumin and great numbers of polymorphonuclear cells. In 

 one or two of the alveoli elongated cells were met with of a fibroblast appearance but 

 new capillaries could not be seen. Section did not pass through one of the abscesses. 

 Spleen, capsule not thickened, malpighian bodies not very sharply marked but could 

 be seen. Pulp cellular, the sinuses not being distinct. Liver cells rather large and 

 cloudy, being separated as if there was slight post mortem change, otherwise liver 

 seemed normal. Kidney, normal except for quite marked post mortem change af- 

 fecting the convoluted tubules. Parotid gland markedlj' congested, the acini being 

 made up of large purple mucus-containing cells which were not very well preserved. 

 No abnormality could be made out. Lymph gland presented much the features de- 

 scribed in previous autopsies, the periphery being packed with Ijonphoid cells, the 

 blood vessels intensely congested, the central sinuses widely dilated and containing 

 moderate numbers of free cells. Section through esophagus showed normal epithelium 

 and normal muscle wall. Section through vomer showed markedly dilated blood 

 vessels in the mucosa, with advanced mucoid change in the glands. There was also 

 edema of the tissue between the glands. Rather numerous and small lymphoid 

 cells were distributed throughout the mucosa. Section through turbinated bone; 

 the high columnar mucosa was fairly well preserved, beneath which came a markedly 

 edematous tissue containing greatly dilated blood vessels, eosinophiles, lymphoid 

 cells and large mononuclears. Sections through several regions of the nasal mucosa 

 showed similar conditions. In some regions the exudate was slightly more abundant 

 than in others, but the same general features prevailed. The glands in this tissue 

 usually contained a purplish material apparently mucus, sometimes a coagulated 

 pinkish material like albumin. 



Autopsy 19. One of the yearlings from Corral VIII had looked rather ill for some 

 time but evidently was convalescing after the use of the alfalfa hay. The animal was 

 still coughing and sneezing; walked stifiSy and had a bloody discharge from the nose. 

 On August 23, the animal was chloroformed and autopsied at once. 



Anato7nical diagnosis. Oestrus avis infection, subacute. Ostertagia inarshalli in 

 stomach; Thyaanosoma actinioides in bile ducts, hepatitis, emaciation. Sarcospo- 

 ridiosis. 



Autopsy S^. Lamb No. 48 was brought from Corral VI, in dying condition. It 

 was seen living on the morning of August 26, but was dead at 2 p.m. and was autop- 

 sied at once. 



Anatomical diagnosis. Acute Oestrus ovis infection. Acute bronchopneumonia. 

 Emaciation. 



Autopsy 25. After two months of drouth a heavy cold rain fell on the evening 

 of August 28. On the following morning lambs 46 from group VII, and 50 from 

 group VIII, were dead. Lamb 46 had always been a heavy feeder and looked like 

 one of the strongest in the pen. Autopsy, 8.15 a.m. 



Anatomical diagnosis. Acute bronchopneumonia. Acute splenic tumor. Cloudy 

 swelling of myocardium, liver and kidney. Acute catarrhal enteritis of lower ileum 

 and cecum. Acute mucopurulent rhinitis and sinusitis with about a dozen young 



