190 SEMI-CENTENNIAL OF TORREY BOTANICAL CLUB 
fusions of Panaeolus venenosus were also administered by way of 
mouth by means of a medicine dropper. Іп all, four experiments 
are recorded in TABLE 3. The results show that these fungi fed to 
guinea pigs will make the animal stupid and appear dazed but 
recovery follows in an hour or two. Feeding of the infusion to 
guinea pigs gave uniform results except in one case, No. 4, re- 
corded in TABLE 3. In all, eight such experiments were made with 
infusions Nos. 2 and 3 and extract No. 5. None, however, 
caused death. The guinea pig in experiment No. 4 (TABLE 3) 
behaved after the feeding as if it had been injected intraperito- 
neally and died five hours after feeding. The autopsy showed 
hemorrhagic areas along the intestinal wall and at the pyloric 
end of the stomach. It is possible that this animal died of pneu- 
monia. It is quite likely that some of the fluid may have gone 
into the lungs. 
It appears from these experiments that feeding of Panaeolus 
venenosus at least causes temporary intoxication with increased 
respiration, but recovery follows within several hours. It has 
been claimed by Ford (1911) that herbivora are not susceptible to 
mushroom toxins when given to them by way of the mouth. 
The effect of an intravenous injection of an infusion of Panaeo- 
lus venenosus was tried on rabbits. Small quantities, 2 c.c. of a 
mixture of 1 c.c. of infusion No. 12 and 20 c.c. of .8 per cent phys- 
iological salt solution, were injected into the marginal vein of the 
right ear. The rate of respiration began to increase shortly after 
the injection until the breathing became labored. The animal 
became deeply intoxicated and its senses dulled; all food offered 
after the injection was refused. Although he began to feed on 
the following day, this intoxicated condition lasted for three 
days, when the effect of the injection began to disappear. Nine 
days later the animal appeared normal. Two further experiments 
were made in which 2 c.c. of solution No. 13 were injected intra- 
venously. Neither proved fatal, although severe intoxication 
was induced, which lasted four to five days, during which time the 
symptoms described above were observed. It is quite likely that 
with larger doses of the infusion No. 13 the results would be 
fatal. З 
