200 SEMI-CENTENNIAL OF TORREY BOTANICAL CLUB 
5. Infusions injected into the circulatory system of the anaes- 
thetized cat produced a decrease in blood pressure followed by an 
increase in blood pressure, from which condition recovery followed. 
The rate of the heart-beat was increased. 
6. Immersion of the gastrocnemius muscle of the frog in infu- 
sions caused the muscle to fatigue sooner than the normal muscle, 
and its working capacity was markedly reduced. 
7. Application of the infusions to the cut end of the sciatic nerve 
of the frog affected the nerve so that its electrical stimulation 
failed to produce a contraction of the gastrocnemius muscle. In 
this respect the infusion acts like cocaine. 
8. Application of the infusions to the vagus nerves of the frog 
and turtle affected the nerves at the point of application so that 
electrical stimulation at that point failed to cause heart inhibition. 
Painting the heart with infusion appeared to have no effect on the 
heart-beat but paralyzed the vagus-nerve terminations. The 
action of the infusion in this differs from the extracts of all other 
fungi so far investigated. 
To Professor Frederic S. Lee and Professor К. A. Harper I 
wish to extend my thanks for many helpful suggestions and criti- 
cisms. 
LITERATURE CITED 
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Clark, E. D., & Kantor, І. І. 1911. Toxicological experiments with 
some of the higher fungi. Mycologia 3: 175-188. f. 1. pl. 52. 
Clark, E. D., & Smith, C. S. 1913. Toxicological studies on mush- 
rooms, Clitocybe illudens and Inocybe infida. Mycologia 5: 2247 
232. Pl. 01. 
Collins, Е. S. 1899. А case of Boletus poisoning. Rhodora І: 21-23. 
Ferry, В. 1911. Étude sur les amanites—Les amanites mortelles. 
Suppl.Rev. Mycol. 1911. 
Ford, W. W. 1906. The toxicological constitution of Amanita phal- 
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Ford, W. W. 1907. A clinical study of mushroom intoxication. 
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