DEVELOPMENT OF EMBRYO. 71 



In the progress of the metamorphosis of the six-hooked cestoid 

 brood into scolices, just treated of, we have also seen that a portion 



with tremulous movements of the ears, twisting of the eyes, convulsive writhings, and 

 bendings of the head and neck to one side or the other, fallings to the ground, twitching 

 of the limbs, gnashing of the teeth, foaming at the mouth, and, in short, all the 

 signs of cerebral convulsions resembling epilepsy, in which, moreover, several of the 

 animals twisted the head principally towards one side or in a circle. 



The first dissection, made on the 22d January, 1854, again showed the small vesicles 

 (£. e. my young Casnuri) observed in my first experiments, as well as the channels of 

 exudation, at the end of which there was sometimes a vesicle, surrounded by a more 

 abundant exudation. Besides these, innumerable minute particles of the size of a grain 

 of sand occurred in the most various situations in the lamb under examination ; for 

 instance, in the oesophagus, heart, diaphragm, peritoneum, &c. In the subsequent 

 dissections the same small vesicles were met with in the latter situations, but it was 

 distinctly seen that instead of growing they had diminished perceptibly in size, in com- 

 parison with those just described, and were, therefore, further advanced in degeneration, 

 so that the organisms situated in these parts may justly be regarded as strayed and 

 arrested young Cestode worms. On the 17th February, forty-two days after the admi- 

 nistration, the vesicles were more deeply imbedded in the brain, as large as small peas, 

 and exhibited the first turbidity, or the commencement of scolex-formation. In the 

 other dissections similar results were obtained. 



On the 5th May, 1854, Professor Haubner again administered mature Tcenia coenurus 

 to eight sheep. On the eighth and tenth days after administration two lambs were 

 examined in vain for the migrating brood. On the twelfth day, a sheep, which was pre- 

 viously chlorotic and ill with vertigo, exhibited the well-known vesicles in the brain; a 

 second died of vertigo on the twentieth, a third on the twenty-first, and a fourth on the 

 twenty-fifth days. Two animals escaped. Of the Tcenia coenurus sent to me by 

 Professor Hauhner on the 5th of May, I forwarded some specimens in white of egg to 

 M. Gurlt, Director of the Veterinary School in Berlin, and here also vertigo made its 

 appearance with exactly the same appearances and results on the eleventh to the four- 

 teenth days after administration. Gurlt also found the str-ayed brood in thediaphragbni 

 and other places. On the 24th of May mature Tcenia coenurus were taken from a dog 

 on the farm of M. Kind, of Kleinbautzen, who has taken a lively interest in the experi- 

 mental elaboration of this question, and administered to two lambs and one full- 

 grown ewe, of which the latter was not affected, one of the lambs was only slightly 

 touched with vertigo, and presented no Ccenuri when dissected eight weeks afterwards, 

 whilst the other, which had apparently escaped, exhihited developed vesicles of Ccenurus 

 at the same period. Encouraged by the success of my consignment to Gurlt, I for- 

 warded from Kleinbautzen, on the 24th of May, mature Tcenice coenurus in white of egg 

 to Van Beneden at Louvain, Leuckart. at Giessen, Gurlt at Berlin, and Eschricht at 

 Copenhagen. The worms arrived safe and sound at these places, on the 2Gth, 

 21st, and 27th May, and twelve, fourteen, and sixteen days after administration the 

 disease showed itself at all these stations, and indeed with the greater rapidity and 

 intensity the longer the road which the Tcenia had to pass, and therefore the later they 

 were administered. 



When, on the 11th June, 1854, I sent fresh Tcenia coenurus to Professor Roll, at the 

 Veterinary School at Vienna, he allowed the proglottides to lie for several days in the 

 rain, and become covered with mould, and only administered them when they began to 



