3)11. T. S. COBBOLD ON CESTOID ENTOZOA. I7l 



cated to tlie Eoyal Society *. During the past year, however, 

 the incessant demands on Mr. Simonds's time (occasioned by 

 the rinderpest epidemic) have left him so little leisure that he has 

 desired me to make use, in any way which I might think fit, of 

 the results thus unitedly obtained. I may remark that the pro- 

 curing and selecting of our experimental materials (such as tri- 

 cbinous flesh and tapeworm-proglottides) generally devolved 

 upon myself, whilst, on the other hand, the actual administra- 

 tions were made either by Mr. Simonds or by Mr. Pritchard, the 

 Assistant Professor and Anatomical Demonstrator at the Eoyal 

 Veterinary College. On these occasions other persons, as well 

 as myself, sometimes rendered aid. I may likewise add that I do 

 not here record certain experiments which Mr. Simonds conducted 

 independently, but only those for which I may rightly be con- 

 sidered exclusively responsible. 



Tcenia mediocanellata. — Exp. 1. This successful case, in which 

 about 8000 tapeworm-larvae were reared in a calf, is already 

 fully reported in the Proceedings of the Eoyal Society for May 

 4, 1865, No. 75, vol. xiv. p. 214. 



Exp. 2. Eour separate worm-feedings were administered to a 

 calf, namely 50 sexually mature proglottides of T. mediocanellata 

 on the 13th of April (1865), 160 proglottides on May 16th, 120 

 proglottides on June 1st, and a final hundred on the 17th of the 

 last-named month. Mr. Simonds states that this animal gave 

 no evidence of helminthic symptoms. On the 2nd of September 

 it was attacked with with rinderpest, and died in 36- hours. I 

 had not myself an opportunity of examining its fiesh, and Mr. 

 Simonds failed to detect any cysticerci in the muscles. 



Exp. 3. In this case the experimental animal was a fine healthy 

 Dutch heifer, about two years old. On the 3rd of March she 

 swallowed 90 proglottides given in tepid water. On the 15th of 

 the same month 108 proglottides were also administered. On 

 the 5th of April another 100 joints were given ; and for a few days 

 after she seemed rather restless, bellowing occasionally. jN'o 

 other symptoms having followed, on the 13th of the succeeding 

 April I made a very careful selection of 200 ripe proglottides, 

 from specimens which I had that day received from Birmingham, 

 through the kindness of Dr. Fleming. Eor some some days the 

 restlessness appeared to increase slightly, and the bellowing con- 

 tinued. In addition there were certain peculiarities of manner 



* " On the Production of the so-called ' Acute Cestode Tuberculosis ' by the 

 administration of the Proglottides of Tcenia mediocanellata." 



