February, 1912.] Annual Address. li 
There is some evidence that these groups are closely allied, 
c 
M.A.S.,C.A.S.and others,—and instruction is given by specialists 
‘in modern methods of malaria research; and their value you 
will readily concede is incalculable. If I had time, there are 
many other febrile conditions which I might mention—7-day 
‘fever, 3-day fever, and Malta fever. 
Kala Jar—1869 in Garo Hills.—The word was first used in 
the Garo or some other Assamese dialect to indicate a well- 
‘tum (Nicolle) 190%. Originally discovered in 1900 by Col. Sir 
William Leishman, .M.C., whilst examining a film taken 
post mortem from a case of what was then called ‘‘ Dum Dum 
fever,’’ the results were published in May 1903. In July 1903 
-Major Donovan, I.M.S., Madras, found similar bodies in blood 
‘taken during life by spleen puncture. 
In July 1904, Major Rogers announced that he had suc- 
-ceeded in observing the development of these parasites into flag- 
ellates by cultivating the blood taken from a case of Kala Zar, 
pointing to an insect carrier: and Patton in Madras later has 
found that these bodies could develop into typical flagellates in 
the bed bug (Cimex rotundatus). We now generally believe 
that this parasite Leishmania—Donovani is the cause of the 
disease known as Kala Zar or tropical Spleenomogaly, and that 
it is probably spread by some insect, but that the particular 
‘carrier is unknown as yet. The treatment of this disease, I 
‘regret to say, remains most unsatisfactory. 
2. Leishmania tropica is found in Delhi boil and Lahore or 
frontier sore. A very strong scientific commission for Kala Zar, 
I have strong reason to believe, will shortly be appointe 
3. Leishmania infantum (Pianese and Nicolle) is febrile 
