Description of two New Algoid Vegetations, one 

 of wliich appears to be the Specific Cause of 



Syphilis, and the other of Gonorrhoea*}. 



By 



J. Ma ^alistoua-y, B. N. S. A. M. M. D. 



Hierzu Tafel I, Figur III, 1-16. 



I. Syphilis. The specific cause of syphilis attacks especially 

 those histological elements, the characteristic, proximate, organic 

 principle of which is either gelatine, osteine, or chondrin. These 

 are connective tissue proper, bone, and cartilage. It first attacks 

 the connective tissue at the points of inoculation, and next the 

 connective tissue of the lymphatic glands, in the vicinity of the 

 primary lesion. After the primary sore or sores have healed, the 

 specific cause may remain, apparently, dormant in the system, for 

 from a few days to some months, or even years. It may then 

 show itself in blotches over a part or the whole surface of the 

 body, resulting frequently in hard swellings of the connective 

 tissue^), which may or may not be followed by a breaking down 

 of the histological elements involved. Sooner or later the poison 

 may attack the periosteal and perichondria! membranes, especially 

 in those parts of the body where they are covered but thinly by 

 the softer tissues. From the periosteal and perichondria! mem- 

 branes the lesions extend to bone and cartilage. 



*) Der Herr Verfasser ersuchte uns um den Abdruck dieser im Jahr 1868 

 erschienenen Arbeit, weil der in Wien erregte Streit über die Aetiologie der 

 Syphilis gezeigt hat, dass Salisbury's Arbeit in Deutschland theils noch 

 ganz unbekannt, theils in Vergessenheit gerathen ist. Salisbury ist der 

 erste Entdecker der begleitenden oder causal wirkenden Organismen der mei- 

 sten Infectionskrankheiteu. 



1) These swellings are caused by a too rapid development of the glue 

 tissue cells, excited by the active growth among them of the Crypta syphilitica, 



IV, 1. 3 



