40 Salisbury, 



Ordered the patient to inhale from an atomizing apparatus every 

 morning the following : Rr. — Tr. iodinii 5j ; potass, chlorat. 5iij ; 

 potass, nitrat. 5iij; tr. conium 3iij; tr. Cimicifugae rac. ^j; aq. 

 camphor. ^\w. — M. S. — Inhale an ounce every evening. Conti- 

 nued this treatment till the neuralgic pains ceased, and then 

 omitted the mercurial, and gave two grains of quinia and twenty 

 drops of tr. ferri chloridi in a full glass of water two hours after 

 each meal. Under this treatment the patient has slowly but stea- 

 dily improved. The nose, throat, and fauces are well, no blot- 

 ches on the surface, and the blood is almost entirely free from 

 the C, syphilitica (July 27 , 1867). In addition to the foregoing 

 treatment, I gave to this patient, to keep up free elimination and 

 to allay febrile symptoms, the following: I|,-. — Potass, acetat. ^jss; 

 potass, nitrat. ^ss; amnion, hydrochlor. 5iij ; aq. camphor. |vij. — M. 

 S. — Take a tablespoonful in a glass of water at night on retiring. 



II. Gonorrhoea. — The epithelial tissue seems to be the 

 only one properly adapted for the development and propagation 

 of the specific poison of gonorrhoea. That portion of this tissue 

 peculiarly susceptible to the disease is the mucous membranes. 

 The parent cells of these surfaces, and especially those of the 

 urinary and genital organs and eye, afford all the necessary con- 

 ditions for the growth and multiplication of the cause. If once 

 planted here, it extends from cell to cell, if not prevented by re- 

 medial means, till it has invaded all the mucous surfaces in con- 

 tinuity with each other. That the gonorrhoeal virus multiplies 

 rapidly under the proper conditions , like the lower cryptogams, 

 has long been noticed. 



As long ago as 1850, I first discovered in gonorrhoeal pus 

 minute sporelike bodies, multiplying by duplicative segmentation 

 in and out of the cells. Although I figured these bodies accura- 

 tely at that time, I was not sufficiently familiar with these nunute 

 cryptogams to determine either their place or significance. 



After having discovered the Crypta syphilitica in the beds 

 of chancres, I was led to examine carefully the tissue invaded 

 by gonorrhoea. Selecting such cases of the disease as had not 

 been subjected to treatment, and where the discharge was copious 

 and the infiammation severe, the patients were directed first to 

 void their urine; the lips of the meatus were then separated, and 

 with the clean edge of a small scalpel I scraped the epithelium 

 from the orifice of the urethra, and placed the scrapings between 



